KEGG   ORTHOLOGY: K23834
Entry
K23834                      KO                                     

Name
ipaH7.8
Definition
E3 ubiquitin-protein ligase IpaH7.8 [EC:2.3.2.27]
Pathway
ko05131  Shigellosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K23834  ipaH7.8; E3 ubiquitin-protein ligase IpaH7.8
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K23834  ipaH7.8; E3 ubiquitin-protein ligase IpaH7.8
Other DBs
COG: COG4886
Genes
SFL: CP0078(ipaH7.8)
SFE: SFxv_4916(ipaH7.8)
SSN: SSON_P058(ipaH7.8)
SBO: SBO_P067(ipaH7.8)
SBC: SbBS512_A0130
SDY: SDY_P038(ipaH7.8)
Reference
  Authors
Buchrieser C, Glaser P, Rusniok C, Nedjari H, D'Hauteville H, Kunst F, Sansonetti P, Parsot C
  Title
The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri.
  Journal
Mol Microbiol 38:760-71 (2000)
DOI:10.1046/j.1365-2958.2000.02179.x
  Sequence
[sfl:CP0078]
Reference
  Authors
Suzuki S, Mimuro H, Kim M, Ogawa M, Ashida H, Toyotome T, Franchi L, Suzuki M, Sanada T, Suzuki T, Tsutsui H, Nunez G, Sasakawa C
  Title
Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages.
  Journal
Proc Natl Acad Sci U S A 111:E4254-63 (2014)
DOI:10.1073/pnas.1324021111
LinkDB

DBGET integrated database retrieval system