KEGG   ORTHOLOGY: K24529
Entry
K24529                      KO                                     
Symbol
mycB
Name
protomycinolide IV desosaminyltransferase [EC:2.4.1.-]
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00934  Mycinamicin biosynthesis, malonyl-CoA + methylmalonyl-CoA => protomycinolide IV => mycinamicin II
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K24529  mycB; protomycinolide IV desosaminyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K24529  mycB; protomycinolide IV desosaminyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.-
     K24529  mycB; protomycinolide IV desosaminyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Glycosyltransferase
   K24529  mycB; protomycinolide IV desosaminyltransferase
Other DBs
RN: R10876
COG: COG1819
Genes
AG: BAC57037(mycB)
Reference
  Authors
Melancon CE 3rd, Takahashi H, Liu HW
  Title
Characterization of tylM3/tylM2 and mydC/mycB pairs required for efficient glycosyltransfer in macrolide antibiotic biosynthesis.
  Journal
J Am Chem Soc 126:16726-7 (2004)
DOI:10.1021/ja043900e
  Sequence
LinkDB

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