KEGG   MODULE: M00016
Entry
M00016            Pathway   Module                                 

Name
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
Definition
(K00928,K12524,K12525,K12526) K00133 K01714 K00215 K00674 (K00821,K14267) K01439 K01778 (K01586,K12526)
Diagram
M00016

Orthology
aspartate kinase [EC:2.7.2.4] [RN:R00480]
K00133  
aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] [RN:R02291]
K01714  
4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] [RN:R10147]
K00215  
4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] [RN:R04198 R04199]
K00674  
2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase [EC:2.3.1.117] [RN:R04365]
N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17] [RN:R04475]
K01439  
succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] [RN:R02734]
K01778  
diaminopimelate epimerase [EC:5.1.1.7] [RN:R02735]
diaminopimelate decarboxylase [EC:4.1.1.20] [RN:R00451]
Class
Pathway modules; Amino acid metabolism; Lysine metabolism
Pathway
map00300  Lysine biosynthesis
map01230  Biosynthesis of amino acids
map01100  Metabolic pathways
Reaction
Compound
C00049  L-Aspartate
C03082  4-Phospho-L-aspartate
C00441  L-Aspartate 4-semialdehyde
C20258  (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate
C03972  2,3,4,5-Tetrahydrodipicolinate
C04462  N-Succinyl-2-L-amino-6-oxoheptanedioate
C04421  N-Succinyl-LL-2,6-diaminoheptanedioate
C00666  LL-2,6-Diaminoheptanedioate
C00680  meso-2,6-Diaminoheptanedioate
C00047  L-Lysine
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