KEGG   MODULE: M00030
Entry
M00030            Pathway   Module                                 

Name
Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Definition
K01655 K17450 K01705 K05824 K00838 K00143 (K00293,K24034) K00290
Diagram
M00030

Orthology
K01655  
homocitrate synthase [EC:2.3.3.14] [RN:R00271]
K17450  
homoaconitase [EC:4.2.1.-] [RN:R03444]
K01705  
homoaconitate hydratase [EC:4.2.1.36] [RN:R04371]
K05824  
homoisocitrate dehydrogenase [EC:1.1.1.87] [RN:R01934]
K00838  
2-aminoadipate transaminase [EC:2.6.1.39] [RN:R01939]
K00143  
L-2-aminoadipate reductase [EC:1.2.1.95] [RN:R03098 R04863 R04390]
saccharopine dehydrogenase (NADP+, L-glutamate forming) [EC:1.5.1.10] [RN:R02315]
K00290  
saccharopine dehydrogenase, L-lysine forming [EC:1.5.1.7] [RN:R00715]
Class
Pathway modules; Amino acid metabolism; Lysine metabolism
Pathway
map00300  Lysine biosynthesis
map01230  Biosynthesis of amino acids
map01100  Metabolic pathways
Reaction
Compound
C00026  2-Oxoglutarate
C00024  Acetyl-CoA
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C04002  (Z)-But-1-ene-1,2,4-tricarboxylate
C05662  Homoisocitrate
C00322  2-Oxoadipate
C00956  L-2-Aminoadipate
C05560  L-2-Aminoadipate adenylate
C05535  alpha-Aminoadipoyl-S-acyl enzyme
C04076  L-2-Aminoadipate 6-semialdehyde
C00449  N6-(L-1,3-Dicarboxypropyl)-L-lysine
C00047  L-Lysine
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