KEGG   MODULE: M00573
Entry
M00573            Pathway   Module                                 

Name
Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin
Definition
K16593 K00652 K19563 K01935 K01012
Diagram
M00573

Orthology
K16593  
pimeloyl-[acyl-carrier protein] synthase [EC:1.14.14.46] [RN:R10123]
K00652  
8-amino-7-oxononanoate synthase [EC:2.3.1.47] [RN:R10124]
K19563  
lysine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.105] [RN:R10699]
K01935  
dethiobiotin synthetase [EC:6.3.3.3] [RN:R03182]
K01012  
biotin synthetase [EC:2.8.1.6] [RN:R01078]
Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
map00780  Biotin metabolism
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
Reaction
Compound
C00173  Acyl-[acyl-carrier protein]
C19845  Pimeloyl-[acyl-carrier protein]
C01092  8-Amino-7-oxononanoate
C01037  7,8-Diaminononanoate
C01909  Dethiobiotin
C00120  Biotin
Reference
  Authors
Lin S, Cronan JE
  Title
Closing in on complete pathways of biotin biosynthesis.
  Journal
Mol Biosyst 7:1811-21 (2011)
DOI:10.1039/c1mb05022b
LinkDB

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