Entry |
|
Name |
AML1-ETO fusion to CEBPA-mediated transcription
|
Definition |
AML1-ETO -| CEBPA => PER2 |
Expanded |
861v2 -| 1050 => 8864 |
Class |
|
Type |
Variant
|
Pathway |
|
Disease |
|
Gene |
861 | RUNX1; runt related transcription factor 1 |
1050 | CEBPA; CCAAT/enhancer binding protein alpha |
8864 | PER2; period circadian clock 2 |
|
Variant |
861v2 (AML1-ETO) AML1-ETO fusion
|
Reference |
|
Authors |
Scandura JM, Boccuni P, Cammenga J, Nimer SD |
Title |
Transcription factor fusions in acute leukemia: variations on a theme. |
Journal |
|
Reference |
|
Authors |
Lutterbach B, Hiebert SW |
Title |
Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation. |
Journal |
|
Reference |
|
Authors |
Koschmieder S, Halmos B, Levantini E, Tenen DG |
Title |
Dysregulation of the C/EBPalpha differentiation pathway in human cancer. |
Journal |
|
Reference |
|
Authors |
Gery S, Gombart AF, Yi WS, Koeffler C, Hofmann WK, Koeffler HP |
Title |
Transcription profiling of C/EBP targets identifies Per2 as a gene implicated in myeloid leukemia. |
Journal |
|
LinkDB |
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