KEGG   NETWORK: N00418
Entry
N00418                      Network                                

Name
HCMV US2/11 to antigen processing and presentation by MHC class I molecules
Definition
(US2,US11) -| MHCI
  Expanded
(K21050,K22786) -| (3105,3106,3107,3133,3134,3135)
Class
nt06129 MHC presentation (viruses)
nt06167 Human cytomegalovirus (HCMV)
Type
Pathogen
Pathway
hsa05163  Human cytomegalovirus infection
Disease
H00368  Cytomegalovirus infection
Gene
3105  HLA-A; major histocompatibility complex, class I, A
3106  HLA-B; major histocompatibility complex, class I, B
3107  HLA-C; major histocompatibility complex, class I, C
3133  HLA-E; major histocompatibility complex, class I, E
3134  HLA-F; major histocompatibility complex, class I, F
3135  HLA-G; major histocompatibility complex, class I, G
Perturbant
K21050 (US2)  US2; HCMV unique short US2 glycoprotein
K22786 (US11)  US11; HCMV membrane glycoprotein US11
Reference
  Authors
Noriega V, Redmann V, Gardner T, Tortorella D
  Title
Diverse immune evasion strategies by human cytomegalovirus.
  Journal
Immunol Res 54:140-51 (2012)
DOI:10.1007/s12026-012-8304-8
Reference
  Authors
Loureiro J, Ploegh HL
  Title
Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions.
  Journal
Adv Immunol 92:225-305 (2006)
DOI:10.1016/S0065-2776(06)92006-9
Reference
  Authors
Horst D, Verweij MC, Davison AJ, Ressing ME, Wiertz EJ
  Title
Viral evasion of T cell immunity: ancient mechanisms offering new applications.
  Journal
Curr Opin Immunol 23:96-103 (2011)
DOI:10.1016/j.coi.2010.11.005
Reference
  Authors
Fortunato EA, McElroy AK, Sanchez I, Spector DH
  Title
Exploitation of cellular signaling and regulatory pathways by human cytomegalovirus.
  Journal
Trends Microbiol 8:111-9 (2000)
DOI:10.1016/S0966-842X(00)01699-1
Reference
  Authors
Loch S, Tampe R
  Title
Viral evasion of the MHC class I antigen-processing machinery.
  Journal
Pflugers Arch 451:409-17 (2005)
DOI:10.1007/s00424-005-1420-8
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