KEGG   NETWORK: N00439
Entry
N00439                      Network                                

Name
HIV Nef to TLR2/4-MAPK signaling pathway
Definition
Nef -| ERK
  Expanded
K22891 -| (5594,5595)
Class
nt06121 TLR signaling (viruses and bacteria)
nt06161 Human immunodeficiency virus type 1 (HIV-1)
Type
Pathogen
Pathway
hsa05170  Human immunodeficiency virus 1 infection
Disease
H01563  HIV infection
Gene
5594  MAPK1; mitogen-activated protein kinase 1
5595  MAPK3; mitogen-activated protein kinase 3
Perturbant
K22891 (Nef)  nef; HIV-1 protein Nef
Reference
  Authors
Yokota S, Okabayashi T, Fujii N
  Title
The battle between virus and host: modulation of Toll-like receptor signaling pathways by virus infection.
  Journal
Mediators Inflamm 2010:184328 (2010)
DOI:10.1155/2010/184328
Reference
  Authors
Tachado SD, Zhang J, Zhu J, Patel N, Koziel H
  Title
HIV impairs TNF-alpha release in response to Toll-like receptor 4 stimulation in human macrophages in vitro.
  Journal
Am J Respir Cell Mol Biol 33:610-21 (2005)
DOI:10.1165/rcmb.2004-0341OC
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