KEGG   NETWORK: N00454
Entry
N00454                      Network                                

Name
HIV Vpr to intrinsic apoptotic pathway
Definition
Vpr -| BAX
  Expanded
K22202 -| 581
Class
nt06131 Apoptosis (viruses and bacteria)
nt06161 Human immunodeficiency virus type 1 (HIV-1)
Type
Pathogen
Pathway
hsa05170  Human immunodeficiency virus 1 infection
Disease
H01563  HIV infection
Gene
581  BAX; BCL2 associated X, apoptosis regulator
Perturbant
K22202 (Vpr)  vpr; HIV-1 virus protein R
Reference
  Authors
Cummins NW, Badley AD
  Title
Mechanisms of HIV-associated lymphocyte apoptosis: 2010.
  Journal
Cell Death Dis 1:e99 (2010)
DOI:10.1038/cddis.2010.77
Reference
  Authors
Gougeon ML
  Title
Apoptosis as an HIV strategy to escape immune attack.
  Journal
Nat Rev Immunol 3:392-404 (2003)
DOI:10.1038/nri1087
LinkDB

DBGET integrated database retrieval system