KEGG   NETWORK: N00461
Entry
N00461                      Network                                

Name
HIV Nef to antigen processing and presentation by MHC class I molecules
Definition
Nef -| MHCI
  Expanded
K22891 -| (3105,3106,3107,3133,3134,3135)
Class
nt06129 MHC presentation (viruses)
nt06161 Human immunodeficiency virus type 1 (HIV-1)
Type
Pathogen
Pathway
hsa05170  Human immunodeficiency virus 1 infection
Disease
H01563  HIV infection
Gene
3105  HLA-A; major histocompatibility complex, class I, A
3106  HLA-B; major histocompatibility complex, class I, B
3107  HLA-C; major histocompatibility complex, class I, C
3133  HLA-E; major histocompatibility complex, class I, E
3134  HLA-F; major histocompatibility complex, class I, F
3135  HLA-G; major histocompatibility complex, class I, G
Perturbant
K22891 (Nef)  nef; HIV-1 protein Nef
Reference
  Authors
Hurley JH, Bonifacino JS
  Title
Nef-arious goings-on at the Golgi.
  Journal
Nat Struct Mol Biol 19:661-2 (2012)
DOI:10.1038/nsmb.2304
Reference
  Authors
Pawlak EN, Dikeakos JD
  Title
HIV-1 Nef: a master manipulator of the membrane trafficking machinery mediating immune evasion.
  Journal
Biochim Biophys Acta 1850:733-41 (2015)
DOI:10.1016/j.bbagen.2015.01.003
Reference
  Authors
Wonderlich ER, Leonard JA, Collins KL
  Title
HIV immune evasion disruption of antigen presentation by the HIV Nef protein.
  Journal
Adv Virus Res 80:103-27 (2011)
DOI:10.1016/B978-0-12-385987-7.00005-1
Reference
  Authors
Laguette N, Bregnard C, Benichou S, Basmaciogullari S
  Title
Human immunodeficiency virus (HIV) type-1, HIV-2 and simian immunodeficiency virus Nef proteins.
  Journal
Mol Aspects Med 31:418-33 (2010)
DOI:10.1016/j.mam.2010.05.003
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