KEGG   NETWORK: N00532
Entry
N00532                      Network                                

Name
HBV HBx to Egr-mediated transcription
Definition
X -> (EGR2,EGR3) -- EP300 => FASLG
  Expanded
K21854 -> (1959,1960) -- 2033 => 356
Class
nt06263 Hepatocellular carcinoma
nt06140 Transcription (viruses)
nt06162 Hepatitis B virus (HBV)
Type
Pathogen
Pathway
hsa05161  Hepatitis B
Disease
H00048  Hepatocellular carcinoma
Gene
1959  EGR2; early growth response 2
1960  EGR3; early growth response 3
2033  EP300; E1A binding protein p300
356  FASLG; Fas ligand
Perturbant
K21854 (X)  X; HBV protein X
Reference
  Authors
Yoo YG, Lee MO
  Title
Hepatitis B virus X protein induces expression of Fas ligand gene through enhancing transcriptional activity of early growth response factor.
  Journal
J Biol Chem 279:36242-9 (2004)
DOI:10.1074/jbc.M401290200
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