KEGG   NETWORK: N00533
Entry
N00533                      Network                                

Name
HBV HBx to Crosstalk between extrinsic and intrinsic apoptotic pathways
Definition
X -> BIRC5 -| CASP9
  Expanded
K21854 -> 332 -| 842
Class
nt06263 Hepatocellular carcinoma
nt06131 Apoptosis (viruses and bacteria)
nt06162 Hepatitis B virus (HBV)
Type
Pathogen
Pathway
hsa05161  Hepatitis B
Disease
H00048  Hepatocellular carcinoma
Gene
332  BIRC5; baculoviral IAP repeat containing 5
842  CASP9; caspase 9
Perturbant
K21854 (X)  X; HBV protein X
Reference
  Authors
Zhang X, Zhang H, Ye L
  Title
Effects of hepatitis B virus X protein on the development of liver cancer.
  Journal
J Lab Clin Med 147:58-66 (2006)
DOI:10.1016/j.lab.2005.10.003
Reference
  Authors
Zhang X, Dong N, Yin L, Cai N, Ma H, You J, Zhang H, Wang H, He R, Ye L
  Title
Hepatitis B virus X protein upregulates survivin expression in hepatoma tissues.
  Journal
J Med Virol 77:374-81 (2005)
DOI:10.1002/jmv.20466
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