KEGG   NETWORK: N00554
Entry
N00554                      Network                                

Name
HBV HBe to TLR4-IRF3/7 signaling pathway
Definition
C -| TICAM2
  Expanded
K23129 -| 353376
Class
nt06263 Hepatocellular carcinoma
nt06121 TLR signaling (viruses and bacteria)
nt06162 Hepatitis B virus (HBV)
Type
Pathogen
Pathway
hsa05161  Hepatitis B
Disease
H00048  Hepatocellular carcinoma
Gene
353376  TICAM2; toll like receptor adaptor molecule 2
Perturbant
K23129 (C)  C; HBV capsid protein
Reference
  Authors
Dandri M, Locarnini S
  Title
New insight in the pathobiology of hepatitis B virus infection.
  Journal
Gut 61 Suppl 1:i6-17 (2012)
DOI:10.1136/gutjnl-2012-302056
Reference
  Authors
Lang T, Lo C, Skinner N, Locarnini S, Visvanathan K, Mansell A
  Title
The hepatitis B e antigen (HBeAg) targets and suppresses activation of the toll-like receptor signaling pathway.
  Journal
J Hepatol 55:762-9 (2011)
DOI:10.1016/j.jhep.2010.12.042
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