KEGG   NETWORK: N00860
Entry
N00860                      Network                                

Name
Yersinia YopP/J to TLR2/4-NFKB signaling pathway
Definition
YopP/J -| IKK
  Expanded
K08598 -| 3551
Class
nt06121 TLR signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05135  Yersinia infection
Disease
H00297  Plague
H00298  Yersiniosis
Gene
3551  IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
Perturbant
K08598 (YopP/J)  yopJ; YopJ protease family
Reference
  Authors
Zhou L, Tan A, Hershenson MB
  Title
Yersinia YopJ inhibits pro-inflammatory molecule expression in human bronchial epithelial cells.
  Journal
Respir Physiol Neurobiol 140:89-97 (2004)
DOI:10.1016/j.resp.2003.12.003
Reference
  Authors
Zhang Y, Ting AT, Marcu KB, Bliska JB
  Title
Inhibition of MAPK and NF-kappa B pathways is necessary for rapid apoptosis in macrophages infected with Yersinia.
  Journal
J Immunol 174:7939-49 (2005)
DOI:10.4049/jimmunol.174.12.7939
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