KEGG   NETWORK: N00864
Entry
N00864                      Network                                

Name
Yersinia YopK to NLRP3 Inflammasome signaling pathway
Definition
YopK -| (NLRP3+PYCARD)
  Expanded
K23477 -| (114548+29108)
Class
nt06139 NLR signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05135  Yersinia infection
Disease
H00297  Plague
H00298  Yersiniosis
Gene
114548  NLRP3; NLR family pyrin domain containing 3
29108  PYCARD; PYD and CARD domain containing
Perturbant
K23477 (YopK)  yopQ; protein YopQ
Reference
  Authors
Brodsky IE, Palm NW, Sadanand S, Ryndak MB, Sutterwala FS, Flavell RA, Bliska JB, Medzhitov R
  Title
A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system.
  Journal
Cell Host Microbe 7:376-87 (2010)
DOI:10.1016/j.chom.2010.04.009
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