KEGG   NETWORK: N00935
Entry
N00935                      Network                                

Name
Escherichia NleF to non-canonical inflammasome signaling pathway
Definition
NleF -| CASP4
  Expanded
K23658 -| 837
Class
nt06139 NLR signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05130  Pathogenic Escherichia coli infection
Disease
H00277  Enterohemorrhagic Escherichia coli (EHEC) infection
H00278  Enteropathogenic Escherichia coli (EPEC) infection
Gene
837  CASP4; caspase 4
Perturbant
K23658 (NleF)  nleF; T3SS secreted effector NleF
Reference
  Authors
Song T, Li K, Zhou W, Zhou J, Jin Y, Dai H, Xu T, Hu M, Ren H, Yue J, Liang L
  Title
A Type III Effector NleF from EHEC Inhibits Epithelial Inflammatory Cell Death by Targeting Caspase-4.
  Journal
Biomed Res Int 2017:4101745 (2017)
DOI:10.1155/2017/4101745
Reference
  Authors
Pallett MA, Crepin VF, Serafini N, Habibzay M, Kotik O, Sanchez-Garrido J, Di Santo JP, Shenoy AR, Berger CN, Frankel G
  Title
Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells.
  Journal
Mucosal Immunol 10:602-612 (2017)
DOI:10.1038/mi.2016.77
LinkDB

DBGET integrated database retrieval system