KEGG   NETWORK: N00941
Entry
N00941                      Network                                

Name
Shigella IpaH9.8 to NOD-NFKB signaling pathway
Definition
(IpaH9.8+TNIP1) -| IKBKG
  Expanded
(K13791+10318) -| 8517
Class
nt06139 NLR signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05131  Shigellosis
Disease
H00299  Shigellosis
Gene
10318  TNIP1; TNFAIP3 interacting protein 1
8517  IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Perturbant
K13791 (IpaH9.8)  ipaH9.8; invasion plasmid antigen
Reference
  Authors
Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M, Sasakawa C
  Title
A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response.
  Journal
Nat Cell Biol 12:66-73; sup pp 1-9 (2010)
DOI:10.1038/ncb2006
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