KEGG   NETWORK: N00944
Entry
N00944                      Network                                

Name
Shigella OspI to TNF-NFKB signaling pathway
Definition
OspI -| UBC13 -> TRAF2
  Expanded
K23827 -| (389898,7334) -> 7186
Class
nt06123 TNF signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05131  Shigellosis
Disease
H00299  Shigellosis
Gene
389898  UBE2NL; ubiquitin conjugating enzyme E2 N like (gene/pseudogene)
7334  UBE2N; ubiquitin conjugating enzyme E2 N
7186  TRAF2; TNF receptor associated factor 2
Perturbant
K23827 (OspI)  ospI; glutamine deamidase
Reference
  Authors
de Jong MF, Liu Z, Chen D, Alto NM
  Title
Shigella flexneri suppresses NF-kappaB activation by inhibiting linear ubiquitin chain ligation.
  Journal
Nat Microbiol 1:16084 (2016)
DOI:10.1038/nmicrobiol.2016.84
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