KEGG   NETWORK: N00946
Entry
N00946                      Network                                

Name
Shigella IpaJ to cGAS-STING signaling pathway
Definition
IpaJ -| ARF1 -> TMEM173
  Expanded
K23832 -| 375 -> 340061
Class
nt06134 CGAS-STING signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05131  Shigellosis
Disease
H00299  Shigellosis
Gene
375  ARF1; ADP ribosylation factor 1
340061  STING1; stimulator of interferon response cGAMP interactor 1
Perturbant
K23832 (IpaJ)  ipaJ; cysteine protease IpaJ
Reference
  Authors
Dobbs N, Burnaevskiy N, Chen D, Gonugunta VK, Alto NM, Yan N
  Title
STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease.
  Journal
Cell Host Microbe 18:157-68 (2015)
DOI:10.1016/j.chom.2015.07.001
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