KEGG   NETWORK: N00947
Entry
N00947                      Network                                

Name
Shigella Ipa4.5 to cGAS-STING signaling pathway
Definition
Ipa4.5 -| TBK1
  Expanded
K23830 -| 29110
Class
nt06134 CGAS-STING signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05131  Shigellosis
Disease
H00299  Shigellosis
Gene
29110  TBK1; TANK binding kinase 1
Perturbant
K23830 (Ipa4.5)  ipaH4.5; E3 ubiquitin-protein ligase IpaH4.5
Reference
  Authors
Zheng Z, Wei C, Guan K, Yuan Y, Zhang Y, Ma S, Cao Y, Wang F, Zhong H, He X
  Title
Bacterial E3 Ubiquitin Ligase IpaH4.5 of Shigella flexneri Targets TBK1 To Dampen the Host Antibacterial Response.
  Journal
J Immunol 196:1199-208 (2016)
DOI:10.4049/jimmunol.1501045
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