KEGG   NETWORK: N01094
Entry
N01094                      Network                                

Name
Escherichia Eae/Tir/TccP to Actin signaling pathway
Definition
Eae -> Tir -> (IRTKS,IRSp53) -> TccP -> WASL -> ARP2/3 -> (ACTB,ACTG1)
  Expanded
K12790 -> K12784 -> (55971,10458) -> K12789 -> 8976 -> (10097+10096+10552+10095+10109+10094+10093+10092+81873) -> (60,71)
Class
nt06135 Cytoskeletal regulation (viruses)
Type
Pathogen
Pathway
hsa05130  Pathogenic Escherichia coli infection
Disease
H00277  Enterohemorrhagic Escherichia coli (EHEC) infection
H00278  Enteropathogenic Escherichia coli (EPEC) infection
Gene
55971  BAIAP2L1; BAR/IMD domain containing adaptor protein 2 like 1
10458  BAIAP2; BAR/IMD domain containing adaptor protein 2
8976  WASL; WASP like actin nucleation promoting factor
10097  ACTR2; actin related protein 2
10096  ACTR3; actin related protein 3
10552  ARPC1A; actin related protein 2/3 complex subunit 1A
10095  ARPC1B; actin related protein 2/3 complex subunit 1B
10109  ARPC2; actin related protein 2/3 complex subunit 2
10094  ARPC3; actin related protein 2/3 complex subunit 3
10093  ARPC4; actin related protein 2/3 complex subunit 4
10092  ARPC5; actin related protein 2/3 complex subunit 5
81873  ARPC5L; actin related protein 2/3 complex subunit 5 like
60  ACTB; actin beta
71  ACTG1; actin gamma 1
Perturbant
K12790 (Eae)  eae; intimin
K12784 (Tir)  tir; translocated intimin receptor
K12789 (TccP)  tccP; Tir-cytoskeleton coupling protein
Reference
  Authors
Lai Y, Rosenshine I, Leong JM, Frankel G
  Title
Intimate host attachment: enteropathogenic and enterohaemorrhagic Escherichia coli.
  Journal
Cell Microbiol 15:1796-808 (2013)
DOI:10.1111/cmi.12179
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