KEGG   NETWORK: N01095
Entry
N01095                      Network                                

Name
Escherichia Map to LPA-GNA12/13-RhoA signaling pathway
Definition
Map -> NHERF1 -> EZR -> RHOA -> ROCK1/2
  Expanded
K12787 -> 9368 -> 7430 -> 387 -> (6093,9475)
Class
nt06135 Cytoskeletal regulation (viruses)
Type
Pathogen
Pathway
hsa05130  Pathogenic Escherichia coli infection
Disease
H00277  Enterohemorrhagic Escherichia coli (EHEC) infection
H00278  Enteropathogenic Escherichia coli (EPEC) infection
Gene
9368  SLC9A3R1; SLC9A3 regulator 1
7430  EZR; ezrin
387  RHOA; ras homolog family member A
6093  ROCK1; Rho associated coiled-coil containing protein kinase 1
9475  ROCK2; Rho associated coiled-coil containing protein kinase 2
Perturbant
K12787 (Map)  map; LEE-encoded effector Map
Reference
  Authors
Berger CN, Crepin VF, Jepson MA, Arbeloa A, Frankel G
  Title
The mechanisms used by enteropathogenic Escherichia coli to control filopodia dynamics.
  Journal
Cell Microbiol 11:309-22 (2009)
DOI:10.1111/j.1462-5822.2008.01254.x
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