KEGG   NETWORK: N01098
Entry
N01098                      Network                                

Name
Yersinia YopT to ITGA/B-RhoGEF-RhoA signaling pathway
Definition
YopT -| RHOA
  Expanded
K08599 -| 387
Class
nt06135 Cytoskeletal regulation (viruses)
Type
Pathogen
Pathway
hsa05135  Yersinia infection
Disease
H00297  Plague
H00298  Yersiniosis
Gene
387  RHOA; ras homolog family member A
Perturbant
K08599 (YopT)  yopT; YopT peptidase
Reference
  Authors
Zumbihl R, Aepfelbacher M, Andor A, Jacobi CA, Ruckdeschel K, Rouot B, Heesemann J
  Title
The cytotoxin YopT of Yersinia enterocolitica induces modification and cellular redistribution of the small GTP-binding protein RhoA.
  Journal
J Biol Chem 274:29289-93 (1999)
DOI:10.1074/jbc.274.41.29289
Reference
  Authors
Aepfelbacher M, Trasak C, Wilharm G, Wiedemann A, Trulzsch K, Krauss K, Gierschik P, Heesemann J
  Title
Characterization of YopT effects on Rho GTPases in Yersinia enterocolitica-infected cells.
  Journal
J Biol Chem 278:33217-23 (2003)
DOI:10.1074/jbc.M303349200
Reference
  Authors
Fueller F, Schmidt G
  Title
The polybasic region of Rho GTPases defines the cleavage by Yersinia enterocolitica outer protein T (YopT).
  Journal
Protein Sci 17:1456-62 (2008)
DOI:10.1110/ps.035386.108
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