KEGG   NETWORK: N01103
Entry
N01103                      Network                                

Name
Yersinia YpkA to IGG-FCGR-RAC signaling pathway
Definition
YpkA -| RAC
  Expanded
K23472 -| (5879,5880,5881)
Class
nt06135 Cytoskeletal regulation (viruses)
Type
Pathogen
Pathway
hsa05135  Yersinia infection
Disease
H00297  Plague
H00298  Yersiniosis
Gene
5879  RAC1; Rac family small GTPase 1
5880  RAC2; Rac family small GTPase 2
5881  RAC3; Rac family small GTPase 3
Perturbant
K23472 (YpkA)  ypkA; serine/threonine protein kinase YpkA
Reference
  Authors
Groves E, Rittinger K, Amstutz M, Berry S, Holden DW, Cornelis GR, Caron E
  Title
Sequestering of Rac by the Yersinia effector YopO blocks Fcgamma receptor-mediated phagocytosis.
  Journal
J Biol Chem 285:4087-98 (2010)
DOI:10.1074/jbc.M109.071035
Reference
  Authors
Prehna G, Ivanov MI, Bliska JB, Stebbins CE
  Title
Yersinia virulence depends on mimicry of host Rho-family nucleotide dissociation inhibitors.
  Journal
Cell 126:869-80 (2006)
DOI:10.1016/j.cell.2006.06.056
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