KEGG   NETWORK: N01107
Entry
N01107                      Network                                

Name
Yersinia YopH to TCR-NFAT signaling pathway
Definition
YopH -| LCK
  Expanded
K23474 -| 3932
Class
nt06120 Calcium signaling (viruses)
Type
Pathogen
Pathway
hsa05135  Yersinia infection
Disease
H00297  Plague
H00298  Yersiniosis
Gene
3932  LCK; LCK proto-oncogene, Src family tyrosine kinase
Perturbant
K23474 (YopH)  yopH; tyrosine-protein phosphatase YopH
Reference
  Authors
Alonso A, Bottini N, Bruckner S, Rahmouni S, Williams S, Schoenberger SP, Mustelin T
  Title
Lck dephosphorylation at Tyr-394 and inhibition of T cell antigen receptor signaling by Yersinia phosphatase YopH.
  Journal
J Biol Chem 279:4922-8 (2004)
DOI:10.1074/jbc.M308978200
Reference
  Authors
de la Puerta ML, Trinidad AG, del Carmen Rodriguez M, Bogetz J, Sanchez Crespo M, Mustelin T, Alonso A, Bayon Y
  Title
Characterization of new substrates targeted by Yersinia tyrosine phosphatase YopH.
  Journal
PLoS One 4:e4431 (2009)
DOI:10.1371/journal.pone.0004431
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