KEGG   NETWORK: N01110
Entry
N01110                      Network                                

Name
Yersinia YopH to ITGA/B-FAK-RAC signaling pathway
Definition
YopH -| BCAR1
  Expanded
K23474 -| 9564
Class
nt06135 Cytoskeletal regulation (viruses)
Type
Pathogen
Pathway
hsa05135  Yersinia infection
Disease
H00297  Plague
H00298  Yersiniosis
Gene
9564  BCAR1; BCAR1 scaffold protein, Cas family member
Perturbant
K23474 (YopH)  yopH; tyrosine-protein phosphatase YopH
Reference
PMID:9767593
  Authors
Black DS, Montagna LG, Zitsmann S, Bliska JB
  Title
Identification of an amino-terminal substrate-binding domain in the Yersinia tyrosine phosphatase that is required for efficient recognition of focal adhesion targets.
  Journal
Mol Microbiol 29:1263-74 (1998)
DOI:10.1046/j.1365-2958.1998.01014.x
Reference
PMID:9171345
  Authors
Persson C, Carballeira N, Wolf-Watz H, Fallman M
  Title
The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions.
  Journal
EMBO J 16:2307-18 (1997)
DOI:10.1093/emboj/16.9.2307
Reference
PMID:9184219
  Authors
Black DS, Bliska JB
  Title
Identification of p130Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions.
  Journal
EMBO J 16:2730-44 (1997)
DOI:10.1093/emboj/16.10.2730
Reference
  Authors
Fallman M, Gustavsson A
  Title
Cellular mechanisms of bacterial internalization counteracted by Yersinia.
  Journal
Int Rev Cytol 246:135-88 (2005)
DOI:10.1016/S0074-7696(05)46004-0
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