KEGG   NETWORK: N01111
Entry
N01111                      Network                                

Name
Yersinia YopH to ITGA/B-FAK-RAC signaling pathway
Definition
YopH -| PTK2
  Expanded
K23474 -| 5747
Class
nt06135 Cytoskeletal regulation (viruses)
Type
Pathogen
Pathway
hsa05135  Yersinia infection
Disease
H00297  Plague
H00298  Yersiniosis
Gene
5747  PTK2; protein tyrosine kinase 2
Perturbant
K23474 (YopH)  yopH; tyrosine-protein phosphatase YopH
Reference
PMID:9171345
  Authors
Persson C, Carballeira N, Wolf-Watz H, Fallman M
  Title
The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions.
  Journal
EMBO J 16:2307-18 (1997)
DOI:10.1093/emboj/16.9.2307
Reference
  Authors
Thinwa J, Segovia JA, Bose S, Dube PH
  Title
Integrin-mediated first signal for inflammasome activation in intestinal epithelial cells.
  Journal
J Immunol 193:1373-82 (2014)
DOI:10.4049/jimmunol.1400145
Reference
  Authors
Fallman M, Gustavsson A
  Title
Cellular mechanisms of bacterial internalization counteracted by Yersinia.
  Journal
Int Rev Cytol 246:135-88 (2005)
DOI:10.1016/S0074-7696(05)46004-0
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