KEGG   REACTION: R00621Help
Entry
R00621                      Reaction                               

Definition
2-Oxoglutarate + Thiamin diphosphate <=> 3-Carboxy-1-hydroxypropyl-ThPP + CO2
Equation
Comment
2-oxoglutarate dehydrogenase complex: oxoglutarate dehydrogenase (see R01700)
TPP-dependent enzymatic reaction (see R00621+R03316)
subsequently R03316
Reaction class
RC00027  C00068_C05381
RC02743  C00026_C05381
Enzyme
Pathway
rn00020  Citrate cycle (TCA cycle)
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Orthology
K00164  2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
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