KEGG   REACTION: R00674
Entry
R00674                      Reaction                               

Name
L-serine hydro-lyase (adding indole; L-tryptophan-forming)
Definition
L-Serine + Indole <=> L-Tryptophan + H2O
Equation
Comment
multi-step reaction
intermediate (2-aminoacrylate Schiff base with PLP)
Reaction class
RC00209  C00078_C00463
RC00210  C00065_C00078
Enzyme
4.2.1.20        4.2.1.122
Pathway
rn00400  Phenylalanine, tyrosine and tryptophan biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K01695  tryptophan synthase alpha chain [EC:4.2.1.20]
K01696  tryptophan synthase beta chain [EC:4.2.1.20]
K06001  tryptophan synthase beta chain [EC:4.2.1.20]
Other DBs
RHEA: 26437
LinkDB

KEGG   RCLASS: RC00209
Entry
RC00209                     RClass                                 

Definition
C8x-C8y:*-C1b:C8x+C8y-C8x+C8y
Reactant pair
Related class
Reaction
Enzyme
2.1.2.8         2.5.1.34        2.5.1.36        2.5.1.39        
2.5.1.80        2.5.1.93        2.5.1.111       2.5.1.119       
2.5.1.121       2.5.1.-         4.1.99.1        4.2.1.20        
4.2.1.122
Pathway
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn00240  Pyrimidine metabolism
rn00380  Tryptophan metabolism
rn00400  Phenylalanine, tyrosine and tryptophan biosynthesis
rn00401  Novobiocin biosynthesis
rn00405  Phenazine biosynthesis
rn00901  Indole alkaloid biosynthesis
rn00943  Isoflavonoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K01667  tryptophanase [EC:4.1.99.1]
K01695  tryptophan synthase alpha chain [EC:4.2.1.20]
K01696  tryptophan synthase beta chain [EC:4.2.1.20]
K03179  4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
K03495  tRNA uridine 5-carboxymethylaminomethyl modification enzyme
K03650  tRNA modification GTPase [EC:3.6.-.-]
K06001  tryptophan synthase beta chain [EC:4.2.1.20]
K06125  4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
K12707  4-hydroxyphenylpyruvate 3-dimethylallyltransferase [EC:2.5.1.111]
K13565  4-hydroxybenzoate geranyltransferase [EC:2.5.1.93]
K14130  tryptophan 4-dimethylallyltransferase [EC:2.5.1.34]
K19796  dCMP hydroxymethylase [EC:2.1.2.8]
K21338  5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase [EC:2.5.1.121]

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