REACTION: R09720
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Entry
R09720 Reaction
Name
(R)-2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate-forming]
Definition
(R)-2-Hydroxybutane-1,2,4-tricarboxylate <=> Homoisocitrate
Equation
C01251
<=>
C05662
Comment
two-step reaction (see
R03444+R04371
)
Reaction class
RC00497
C01251_C05662
Enzyme
4.2.1.114
Pathway
rn01100
Metabolic pathways
rn01120
Microbial metabolism in diverse environments
rn01210
2-Oxocarboxylic acid metabolism
rn01230
Biosynthesis of amino acids
rn01240
Biosynthesis of cofactors
Module
M00433
Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
M00608
2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Orthology
K16792
methanogen homoaconitase large subunit [EC:
4.2.1.114
]
K16793
methanogen homoaconitase small subunit [EC:
4.2.1.114
]
Other DBs
RHEA:
32306
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