Acidaminococcus fermentans: Acfer_0906
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Entry
Acfer_0906 CDS
T01151
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
afn
Acidaminococcus fermentans
Pathway
afn00230
Purine metabolism
afn01100
Metabolic pathways
afn01110
Biosynthesis of secondary metabolites
Module
afn_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
afn00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Acfer_0906
Enzymes [BR:
afn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
Acfer_0906
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-ProteinID:
ADB47291
UniProt:
D2RJN9
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Position
1040345..1044121
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AA seq
1258 aa
AA seq
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MSDKIRRVFVEKKKEYAVEAAGLCSDLQQTLGLKNLKSVRILNRYDLEGLSDEEYQEARS
LVLSEAPVDVVRDEEVEIPAGIRSFAVELLPGQYDQREDFAAQCIQAITQGQRPIVAAAK
VFLLEGDLSDADFEKIKKYCINPVEAQEAAIEKPETLDMTWDVPKPVAVLDGFRSLDRKG
LEDFLNQQELAMSLEDLAFIQEYFQKENRDPSITEIKVLDTYWSDHCRHTTFETKLENVS
ITDGVYTQPVAEAYDLYKKDRDFVYGADTKRPITLMDMACLATKKLKKEGKIPDLDASEE
INACSIVAPIDVDGKKEDWLVMFKNETHNHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQ
AMRVTGSGDPRTPYEQTLKGKLPQRKITLGAAAGYSSYGNQIGLATGSVEEYYHPKFVAK
RMEVGAVIGAAPRDAVVRERPAAGDLIVLLGGRTGRDGMGGATGASKEHTTKSLSECGAE
VQKGNAPNERKIQRLFRDPEVTRLIKRCNDFGAGGVSVAIGELAPGLVINLDKVPKKYEG
LDGTELAISESQERMAVCIAASDLDKFMAAAAKENLEATVVAEVAEDPRLVMYWRGEKIV
DLSRAFLDTNGIPQKSNVVVDGVEETSPFNSTPEEVEGKKDIKEAWLANLDRLNVCSEEG
LGERFDGSIGRGSVLMPYGGRNQLTRTEGMAARLPVLHGKTNATSIMASGYDPNVCCWSP
YHGAMYAVVEAVCRAAAMGADPKKLRLSMQEYFPKLHTEHTWGRPFAALLGAYKACCELE
LPAIGGKDSMSGTFMDLEVPPSLICFAVGVMDGRDTISNEFKQAGNTVVFIPVPCDEHEV
VDYPALRTLLDSVHKAILGKRILTAGVVKEGGVAAAISSMCLGNGLGFGFVKPFLHEECL
FTLQPGGFLVEMAPGADPDKVFAGNDFLVLGSLTDDGKVTVNDTAITLDEIKAAYTRTLE
GVFPSVVKDSGKEICRMPYYRNDLPLTAPYNVAQPRVFIPVFPGLNCEYDTAAAFEAAGA
KADICVIRNLTPEAIKESVEEMAKRIKEAQILAIPGGFSASDEPEGSGKFIATMFRNPAL
KEAVLDLLYNRDGLALGICNGFQALIKLGLVPYGDIRPLTETSPTLTFNTIGRHISRMVE
TKVVSNKSPWLALTEPGDIHTVAVSHGEGRFVATEEEIKKLFANGQVATQYVNQAGDPTM
ESPYNPNGSLYAIESITSPDGRVLGKMGHTERFTEGLMKNIPGNKLQPLFLGGVQYFK
NT seq
3777 nt
NT seq
+upstream
nt +downstream
nt
atgagcgacaagattagaagagtatttgtggagaagaagaaagaatatgctgtggaagca
gcaggtctgtgttccgatctccagcagaccctggggctgaagaatctgaaaagcgtccgg
atcctgaaccggtacgatctggagggcctcagtgacgaagaataccaggaagccagaagc
ctggtgctcagcgaagcaccggtggatgtggtccgggatgaagaagtggaaatccctgcc
ggcatccgcagctttgccgtggaactgctcccgggccagtacgaccagagagaagatttt
gccgcccagtgcatccaggccatcacccagggacagcggcccattgtggcagccgccaaa
gtgttcctgctggaaggtgacctgtccgacgccgactttgaaaaaatcaagaaatactgc
atcaacccggtggaagcccaggaagcggccattgaaaagccggaaaccctggatatgacc
tgggatgtgcccaaacccgtagccgtgctggacggcttccggagcctggacagaaaaggc
ctggaagacttcctgaaccagcaggaactggccatgagcctggaagacctggcctttatc
caggaatacttccagaaagaaaaccgggatccctccattaccgaaatcaaggtgctggat
acctactggtccgaccactgccggcacaccacctttgaaaccaaactggaaaacgtttcc
atcaccgacggcgtatacacccagccggtggcggaagcctatgacctgtacaagaaagac
cgggattttgtctacggtgccgacaccaaacgccccatcaccctgatggacatggcatgc
ctggccaccaagaagctgaaaaaggaagggaagatccccgacctggatgcttccgaagaa
atcaacgcctgcagcatcgtggcccccattgacgtggacggcaaaaaagaagactggctg
gtgatgttcaagaacgaaacccacaaccatcccaccgaaatcgaacccttcggcggtgcc
gccacctgcctgggcggggccatccgggatcccctcagcggccggagctatgtgtaccag
gccatgcgggtcaccgggtccggcgatccccgtaccccttatgaacagaccctgaaaggc
aagctgccccagcggaagatcaccctgggcgctgcagccggctacagctcctacggcaac
cagatcggtctggccaccggttccgtggaagaatactaccatcccaaattcgtggccaag
agaatggaagtgggggccgtcatcggggctgctccccgggacgccgtggtccgggaacgt
ccggctgcgggcgacctgatcgtgctgctgggcggccgtaccggccgtgacggcatgggc
ggcgccaccggtgcctccaaggaacacaccaccaaatccctcagcgaatgcggtgcagaa
gtccagaaggggaatgcccccaacgaacggaagatccagcggctgttccgggatccggaa
gtgacccggctgatcaaacggtgcaacgacttcggggccggcggggtatccgtggccatc
ggcgaactggcaccgggcctggtaatcaacctggacaaggtgcccaagaaatacgaaggc
ctggacggcacggaactggccatcagtgaatcccaggaacggatggccgtgtgcatcgcc
gccagcgacctggacaaattcatggccgctgccgccaaggaaaacctggaagccacggtg
gtggcggaagtggcggaagatccccgtctggtgatgtactggagaggggaaaaaatcgtg
gacctgtcccgggctttcctggataccaacggcattccccagaaatccaatgtggtggtg
gacggagtggaagaaacctctcccttcaacagcaccccggaagaagtggaaggcaaaaag
gatatcaaagaagcctggctggccaacctggaccggctcaatgtgtgcagtgaagagggc
ctgggcgaacggttcgacggctccatcggccggggcagcgtactgatgccctacggcggc
cggaaccagctgacccgcaccgaaggcatggcggcccgtctgccggtactccacggcaag
accaacgccacctccatcatggccagcggctatgatcccaacgtgtgctgctggagcccg
taccacggggccatgtacgccgtggtggaagccgtgtgccgggctgcggccatgggggcc
gacccgaagaaactgcgtctttccatgcaggaatacttccccaaactccatacggaacat
acctggggccggcctttcgccgctctcctgggtgcctataaagcctgctgcgaactggaa
ctgccggccatcggcggcaaggattccatgagcggcaccttcatggacctggaagttccg
ccttccctgatctgcttcgccgtaggggttatggacggccgggataccatctccaacgaa
ttcaaacaggccggcaacacagtggtgttcatcccggtaccctgcgatgaacacgaagtg
gtggattaccccgccctgcggaccctcctggacagcgtccacaaagccatcctgggcaaa
cggattctcaccgccggcgtggtgaaggaagggggcgtggcagccgccatctcctccatg
tgcctgggcaacggtctgggcttcgggttcgtgaaacccttcctccatgaggaatgcctg
ttcaccctgcagcccggcgggttcctggtggaaatggcaccgggggccgatccggacaaa
gtcttcgccggcaatgatttcctggtgctgggctccctgaccgacgacggcaaagtcacc
gtcaacgacaccgccatcaccctggacgaaatcaaagccgcctatacccgcaccctggaa
ggggtattcccctctgtggtgaaggattccggcaaggaaatctgccggatgccctattac
cggaatgacctgcccctgaccgcgccctacaacgtggcccagcctcgggtgttcattccc
gtattcccgggcctgaactgcgaatacgacaccgctgccgcctttgaagcagccggtgcc
aaagccgatatctgtgtgatccggaacctgactccggaagccatcaaggaaagcgtggaa
gaaatggccaaacggatcaaagaagcccagatcctggccattcccggcgggttctccgcc
agtgacgaaccggaaggatccggcaagttcatcgccaccatgttccggaacccggccctg
aaggaagcggtgctggatctcttgtacaaccgggacggcctggccctggggatctgcaac
ggtttccaggccctgatcaaactgggtctggtgccctatggagacatccgtccgctgacg
gaaacctctcccaccctgaccttcaacaccatcggccggcacatttcccggatggtggaa
acgaaagtggtttccaacaaatctccgtggctggcactcaccgaacccggtgacatccac
acggtagccgtatcccacggggaaggccggttcgtggccacggaagaagagatcaagaaa
ctcttcgccaacggccaggtggccacccagtatgtgaaccaggcaggggatcccaccatg
gaaagcccctacaaccccaacggctccctgtatgccatcgaaagcatcaccagccccgac
gggcgtgtgctgggcaagatgggccacaccgaacggttcaccgagggtctcatgaagaac
atcccggggaacaaactgcagcctctgttcctgggcggcgtgcagtacttcaagtaa
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