| Entry |
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| Symbol |
tylHI
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| Name |
(KEGG) 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase (EC:1.14.15.34)
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| KO |
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| Taxonomy |
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| Lineage |
Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces |
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| Organism |
Streptomyces fradiae
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| Module |
| 1906_M00773 | Tylosin biosynthesis, methylmalonyl-CoA + malonyl-CoA => tylactone => tylosin |
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| AA seq |
420 aa
MSSSGDARPSQKGILLPAARANDTDEAAGRRSIAWPVARTCPFSPPEQYAALRAEEPIAR
AELWDGAPVWLISRQDHVRALLADPRVSIHPAKLPRLSPSDGEAEASRSLLTLDPPDHGA
LRGHFIPEFGLRRVRDVRPSVEQIVTGLLDDLTARGDEADLLADFALPMATQVICRLLDI
PYEDRDYFQERTEQATRPAAGEEALEALLELRDYLDRLISGKTGRESGDGMLGSMVAQAR
GGGLSHADVLDNAVLLLAAGHETTASMVTMSVLVLLQHPTAWRELTVNPGLLPGAVDELL
RYLSIADGLRRSATADIEIDGHTIRAGDGLVFLLAAANRDEAVFSEPEAFDIHRSARRHV
AFGYGPHQCLGQNLARMELEVALGAVLERLPALRPTTDVAGLRLKSDSAVFGVYELPVAW |
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| Reference |
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| Authors |
Fouces R, Mellado E, Diez B, Barredo JL |
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| Title |
The tylosin biosynthetic cluster from Streptomyces fradiae: genetic organization of the left region. |
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| Journal |
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| Reference |
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| Authors |
Baltz RH, Seno ET |
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| Title |
Properties of Streptomyces fradiae mutants blocked in biosynthesis of the macrolide antibiotic tylosin. |
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| Journal |
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