KEGG   Addendum: AAK73512
Entry
AAK73512          CDS       T10000                                 
Symbol
amphA
Name
(KEGG) polyene macrolide polyketide synthase, loading module
  KO
K16382  polyene macrolide polyketide synthase, loading module
Taxonomy
TAX:40318
  Lineage
Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces nodosus
SSDB
Motif
Pfam: ketoacyl-synt Acyl_transf_1 Ketoacyl-synt_C PKS_DH_N PS-DH KAsynt_C_assoc PP-binding Thiolase_N
Other DBs
NCBI-ProteinID: AAK73512
GB: AF357202
UniProt: Q93NW8
LinkDB
AA seq 1412 aa
MTIGANDDPVVVVGMACRFPGGVEGPEDLWELVRDGRDATGPFPGDRGWDLAALTGDGPD
HSVTHRGGFLAAAADFDAGFFGMSPREAVSTDPQQRLVLETSWEALEHAGIDPHTLRGTR
TGVFVGTNGQDYATVTNASREDLTGHALTGLSPSIASGRLAYFLGLEGPAVTLDTASSSS
LVALHYALRSLRSGECTTALAGGVTVMSTPVGFIAYTRQGGLAADGRCKVFSDDADGTTW
AEGAGMIVLERLSTARAAGHRVLAVLRGSAVNQDGASDGLTAPSGPAQERLVREALADAG
LGPADIDLVEAHGTGTRLGDPIEARALLATYGQDRDGGQPLRLGSLKSNIGHAQAAAGIG
GLIKAVQALRHGLMPETLNLSTPTRHVDWSAGAVELLTEALPWPGTGRPRRAAVSSFGIS
GTNAHVIVEEAPTTDPAAAVPAGPAHRDVASAADSAARPAALAGEPADTSAPAAVDAGPA
DRPVTPAARLAALVPAADAVAWPVSGASPEALDAQVERLTSFVRDHPGADPLDIGHSLAT
GRAALRHRAVLVPSGDGVVEIARGEAAPRTTAVLFSGQGSQRLGMGRELAARFPVFAKAL
DTVLAALDPQLERPVRSVMWGEDPAELDRTGWTQPALFAFEVALYRLAESFGLRPDAVGG
HSVGEIAAAHIAGVLSLEDAARLVAARATLMQALPEGGAMSAVEASEDEVLPLLDGDVSL
AAVNGPTAVVVSGAEDAVERVSAHFAAQGRRTSRLAVSHAFHSPLMEPMLDAFRDVVAGL
TFHEPTLPVMSNLTGELAGAEIATPEYWVRHVRGTVRFADGVTALREHGTDLLVELGPGS
VLTALARTVLGPDTPGAPVDVVPTLRKDQPEERALTAALGRLHVLGATVDWSALYTGTGA
RRTDLPTYAFQHARYWPAPGRPGTGTAGGGHPLLGPAVELADGGTVSGATLSVATHPWLA
DHVVAGRVLLPAAVLVELAVRAGDDTGCDVLHELALVEAPVLEAGDTLDLQVRVGSADEA
GRRTLTVHSRPGNSPAEPWTQRAGGLLGTAPRTAAAPDTSFAVAWPPPGAEPLDLGDHYE
RLVDDGFDLGPAFRGLRTAWRHDGAFLAEVELPAGTTDDPGAYGVHPALLDAARHAALTT
TGTLPVAWHGVRLHAVGATALRVRIHSADDGALTLTAADVTGAPVFTAEAVVVRQLTEQE
RTAPRPLTRAWHQDTATPRRTRPVAAAPGAAAEPSASSAPDSFAAEAAALAPAERERRLI
GLVRTQAAAVLGHQGPDAVGPRAVFKELGFDSLAGVELSDRLTALTGLRLPATLVFNFPT
PELAARRIGELLVVSGSSPQGSCDDELTRFEAVVQTLSADDPGRQAVADRLDALVASLRR
NSAPQENFSDEDIESVSVDRLLDIIDEEFEIS
Reference
PMID:11451671
  Authors
Caffrey P, Lynch S, Flood E, Finnan S, Oliynyk M
  Title
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.
  Journal
Chem Biol 8:713-23 (2001)
DOI:10.1016/S1074-5521(01)00046-1

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