Acinonyx jubatus (cheetah): 106987995 Help Entry 106987995         CDS       T04657                                  Gene name CASP8 Definition (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism aju  Acinonyx jubatus (cheetah) Pathway aju01524   Platinum drug resistance aju04115   p53 signaling pathway aju04210   Apoptosis aju04215   Apoptosis - multiple species aju04217   Necroptosis aju04620   Toll-like receptor signaling pathway aju04621   NOD-like receptor signaling pathway aju04622   RIG-I-like receptor signaling pathway aju04625   C-type lectin receptor signaling pathway aju04657   IL-17 signaling pathway aju04668   TNF signaling pathway aju04932   Non-alcoholic fatty liver disease aju05010   Alzheimer disease aju05016   Huntington disease aju05022   Pathways of neurodegeneration - multiple diseases aju05132   Salmonella infection aju05134   Legionellosis aju05142   Chagas disease aju05145   Toxoplasmosis aju05152   Tuberculosis aju05160   Hepatitis C aju05161   Hepatitis B aju05162   Measles aju05163   Human cytomegalovirus infection aju05164   Influenza A aju05165   Human papillomavirus infection aju05167   Kaposi sarcoma-associated herpesvirus infection aju05168   Herpes simplex virus 1 infection aju05169   Epstein-Barr virus infection aju05170   Human immunodeficiency virus 1 infection aju05200   Pathways in cancer aju05203   Viral carcinogenesis aju05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:aju00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     106987995 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     106987995 (CASP8)    04215 Apoptosis - multiple species     106987995 (CASP8)    04217 Necroptosis     106987995 (CASP8)    04115 p53 signaling pathway     106987995 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     106987995 (CASP8)    04621 NOD-like receptor signaling pathway     106987995 (CASP8)    04622 RIG-I-like receptor signaling pathway     106987995 (CASP8)    04625 C-type lectin receptor signaling pathway     106987995 (CASP8)    04657 IL-17 signaling pathway     106987995 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     106987995 (CASP8)    05203 Viral carcinogenesis     106987995 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     106987995 (CASP8)    05016 Huntington disease     106987995 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     106987995 (CASP8)   09166 Cardiovascular disease    05416 Viral myocarditis     106987995 (CASP8)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     106987995 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     106987995 (CASP8)    05134 Legionellosis     106987995 (CASP8)    05152 Tuberculosis     106987995 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     106987995 (CASP8)    05161 Hepatitis B     106987995 (CASP8)    05160 Hepatitis C     106987995 (CASP8)    05164 Influenza A     106987995 (CASP8)    05162 Measles     106987995 (CASP8)    05168 Herpes simplex virus 1 infection     106987995 (CASP8)    05163 Human cytomegalovirus infection     106987995 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     106987995 (CASP8)    05169 Epstein-Barr virus infection     106987995 (CASP8)    05165 Human papillomavirus infection     106987995 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     106987995 (CASP8)    05142 Chagas disease     106987995 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     106987995 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:aju01002]     106987995 (CASP8) Enzymes [BR:aju01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      106987995 (CASP8) Peptidases and inhibitors [BR:aju01002]  Cysteine peptidases   Family C14: caspase family    106987995 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  106987995 NCBI-ProteinID:  XP_014941844 UniProt:  A0A6J1YW13 LinkDB All DBs Position Unknown AA seq 479 aa AA seqDB search MDFSKCLYNIGEQLGSDELASLKFLSLDYIPQKKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLFNYLNTSKEAMQQELQIPGRAQIPPYRVMLFQISEDVNKLELRSF KFLLSQEISRCKVDDDMNLLDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREGRMSLQRSPDELSNGEESLAMMALSDSLEEQDSESQTSDKVYRMKSKPRGYCLIFN NYDFSRARKDVPKLQNIKDRNGTNFDAEALSKTFSELHFEIVNFKDSTAKTICEVLKSYQ RMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLAGKPKIFFIQAC QGDNYQRGIAVETDSEQKEDYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNPTEGTW YIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDKKNMGKQMPQPTFTLRKKLFFPLN NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atggatttcagtaaatgtctgtataatattggggaacagctgggcagtgacgagctggcc tccctcaaattcctgagcctggactacatcccacaaaagaagcaagaacccatcaaagat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggacctgctgttcaactacctgaac accagcaaggaagcgatgcagcaggagcttcagataccaggcagagcccagatccctccc tacagggtcatgctttttcagatttcagaagatgtaaacaaattggaattgaggtcgttt aagtttcttttgagccaggagatctccagatgtaaagtggatgatgatatgaacttgctt gatattttcatagagatggaaaagagggtcatcctaggggaaagaaatttggacactctg aaaagaatctgtgaccaaatcaacaagagcctgctgaagaaaatcactgattatgaagaa ttaagcagagagggaagaatgagccttcaaagaagtccagatgaattgtcaaatggggag gaatccctggcaatgatggcattatcggactctctagaagaacaggacagtgagtcacag acatcggacaaagtttaccgaatgaaaagcaaacctcgcggatattgtttgatctttaac aattatgattttagcagagcacggaaggatgtgcccaaacttcagaacattaaggatagg aatggaacaaacttcgatgcagaagctttgagtaagacctttagtgagcttcattttgag attgtgaatttcaaagactctacagcaaagacaatctgtgaagttctgaaatcctaccaa agaatggaccataataacaaagattgcttcatctgctgtatcctctcccatggagacaaa ggcattatttatggctctgatgggcaggaagcccccatctatgagctgacttcttacttc actggttcaaagtgcccttcccttgcaggcaagcccaaaatcttttttattcaggcttgt caaggggataactaccagagaggtatagctgttgagactgactccgaacagaaggaagac tacttagaaatggactcatcatttcagaagagatatatcccagatgaggctgattttctg ctggggatggccactgtgaacaactgtgtttcctaccgaaaccctacggaggggacctgg tatatccagtcactttgccagagcctaagagaaagatgtcctaggggcgaagatatcctc accatccttactgaggtgaactttgaagtgagcaataaggatgacaagaaaaacatgggg aaacaaatgccacaacctactttcacactgaggaaaaaactcttcttccctcttaattga

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