KEGG   Acinonyx jubatus (cheetah): 106989109
Entry
106989109         CDS       T04657                                 

Gene name
ADCY3
Definition
(RefSeq) adenylate cyclase type 3 isoform X1
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
aju  Acinonyx jubatus (cheetah)
Pathway
aju00230  Purine metabolism
aju01100  Metabolic pathways
aju01522  Endocrine resistance
aju04015  Rap1 signaling pathway
aju04020  Calcium signaling pathway
aju04022  cGMP-PKG signaling pathway
aju04024  cAMP signaling pathway
aju04062  Chemokine signaling pathway
aju04072  Phospholipase D signaling pathway
aju04114  Oocyte meiosis
aju04211  Longevity regulating pathway
aju04213  Longevity regulating pathway - multiple species
aju04261  Adrenergic signaling in cardiomyocytes
aju04270  Vascular smooth muscle contraction
aju04371  Apelin signaling pathway
aju04540  Gap junction
aju04611  Platelet activation
aju04713  Circadian entrainment
aju04714  Thermogenesis
aju04723  Retrograde endocannabinoid signaling
aju04724  Glutamatergic synapse
aju04725  Cholinergic synapse
aju04727  GABAergic synapse
aju04740  Olfactory transduction
aju04750  Inflammatory mediator regulation of TRP channels
aju04911  Insulin secretion
aju04912  GnRH signaling pathway
aju04913  Ovarian steroidogenesis
aju04914  Progesterone-mediated oocyte maturation
aju04915  Estrogen signaling pathway
aju04916  Melanogenesis
aju04918  Thyroid hormone synthesis
aju04921  Oxytocin signaling pathway
aju04923  Regulation of lipolysis in adipocytes
aju04925  Aldosterone synthesis and secretion
aju04926  Relaxin signaling pathway
aju04927  Cortisol synthesis and secretion
aju04928  Parathyroid hormone synthesis, secretion and action
aju04934  Cushing syndrome
aju04935  Growth hormone synthesis, secretion and action
aju04962  Vasopressin-regulated water reabsorption
aju04970  Salivary secretion
aju04971  Gastric acid secretion
aju04972  Pancreatic secretion
aju04976  Bile secretion
aju05032  Morphine addiction
aju05163  Human cytomegalovirus infection
aju05166  Human T-cell leukemia virus 1 infection
aju05200  Pathways in cancer
aju05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:aju00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    106989109 (ADCY3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    106989109 (ADCY3)
   04371 Apelin signaling pathway
    106989109 (ADCY3)
   04020 Calcium signaling pathway
    106989109 (ADCY3)
   04072 Phospholipase D signaling pathway
    106989109 (ADCY3)
   04024 cAMP signaling pathway
    106989109 (ADCY3)
   04022 cGMP-PKG signaling pathway
    106989109 (ADCY3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    106989109 (ADCY3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    106989109 (ADCY3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    106989109 (ADCY3)
   04062 Chemokine signaling pathway
    106989109 (ADCY3)
  09152 Endocrine system
   04911 Insulin secretion
    106989109 (ADCY3)
   04923 Regulation of lipolysis in adipocytes
    106989109 (ADCY3)
   04912 GnRH signaling pathway
    106989109 (ADCY3)
   04913 Ovarian steroidogenesis
    106989109 (ADCY3)
   04915 Estrogen signaling pathway
    106989109 (ADCY3)
   04914 Progesterone-mediated oocyte maturation
    106989109 (ADCY3)
   04921 Oxytocin signaling pathway
    106989109 (ADCY3)
   04926 Relaxin signaling pathway
    106989109 (ADCY3)
   04935 Growth hormone synthesis, secretion and action
    106989109 (ADCY3)
   04918 Thyroid hormone synthesis
    106989109 (ADCY3)
   04928 Parathyroid hormone synthesis, secretion and action
    106989109 (ADCY3)
   04916 Melanogenesis
    106989109 (ADCY3)
   04925 Aldosterone synthesis and secretion
    106989109 (ADCY3)
   04927 Cortisol synthesis and secretion
    106989109 (ADCY3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    106989109 (ADCY3)
   04270 Vascular smooth muscle contraction
    106989109 (ADCY3)
  09154 Digestive system
   04970 Salivary secretion
    106989109 (ADCY3)
   04971 Gastric acid secretion
    106989109 (ADCY3)
   04972 Pancreatic secretion
    106989109 (ADCY3)
   04976 Bile secretion
    106989109 (ADCY3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    106989109 (ADCY3)
  09156 Nervous system
   04724 Glutamatergic synapse
    106989109 (ADCY3)
   04727 GABAergic synapse
    106989109 (ADCY3)
   04725 Cholinergic synapse
    106989109 (ADCY3)
   04723 Retrograde endocannabinoid signaling
    106989109 (ADCY3)
  09157 Sensory system
   04740 Olfactory transduction
    106989109 (ADCY3)
   04750 Inflammatory mediator regulation of TRP channels
    106989109 (ADCY3)
  09149 Aging
   04211 Longevity regulating pathway
    106989109 (ADCY3)
   04213 Longevity regulating pathway - multiple species
    106989109 (ADCY3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    106989109 (ADCY3)
   04714 Thermogenesis
    106989109 (ADCY3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106989109 (ADCY3)
  09165 Substance dependence
   05032 Morphine addiction
    106989109 (ADCY3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    106989109 (ADCY3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    106989109 (ADCY3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    106989109 (ADCY3)
   05163 Human cytomegalovirus infection
    106989109 (ADCY3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    106989109 (ADCY3)
Enzymes [BR:aju01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     106989109 (ADCY3)
SSDB
Motif
Pfam: Guanylate_cyc AC_N HNOBA NCE101 Peptidase_S49_N
Other DBs
NCBI-GeneID: 106989109
NCBI-ProteinID: XP_026889120
UniProt: A0A6J1X710
LinkDB
Position
Unknown
AA seq 1152 aa
MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVYSSDKLAPLVVAGMGLLLDIL
LFVLCKKGLLPDRVTRKVVPYLLWLLITAQIFSYLGLNFARAHAASDTVGWQTFFVFSFF
ITLPLSLSPIVVISVVSCVVHTLVLGVTVAQQQQDGLKGRHLLREILANVCLYLCAIMVG
VMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES
QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ
LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV
LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCE
YLDEKGIETYLIIASKPEVKKTAAQHGLDGPALLNGAPASSKPSSPALIETKEPNGSIHT
SGSTSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA
QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTN
YMTFVVGEVLLLILTVCSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN
VVDMLSCLQYHTGPVNSTAGTEAEDGCVENPKYYSYVAVLSLIATIMLVQVSHMVKLTLM
LLVTGAVAVINIYAWRPIFDEYDRKRFQEHDFPAVAFEKMQVLSTPGLNGTDRLPLVPSK
YSMTVMIFIMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH
VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF
DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFANSNKEEKSDRERWQHLADLADF
ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV
MGNIQVCPARAEHVLRPRDRAQSQNRGCFATCYCLLSVGPGYQVGVFGRLKARVERDASG
EGREYFDPISKI
NT seq 3459 nt   +upstreamnt  +downstreamnt
atgccaaggaaccagggcttttcggagcccgagtactcggctgagtactccgccgaatac
tcggtcagcctgccctctgaccccgaccgcggggtgggccggacccatgaaatctctgtc
cggaactcgggatcctgcctctgcctgcctcgattcatgcggctgaccttcgtgcccgag
tccttggagaacttgtaccagacctacttcaaacggcagcgccatgagacgctgctggtg
ctggtggtgtttgcggccctcttcgactgctacgtggtggtcatgtgcgcggtggtctac
tccagcgacaagctggctcccctggtcgtcgctgggatgggactgctgttggacatcctc
ctcttcgtgctctgcaaaaaggggcttctccccgaccgtgtcacccggaaagtggtgccc
tacctgctgtggctgctgataactgcccagattttctcctacctgggcctgaactttgcc
cgcgcgcatgcggccagcgacacggtgggctggcagactttctttgtcttctccttcttc
atcacgctgcccctcagcctcagccccatcgtcgtcatctccgtggtctcctgtgttgtg
cacacactcgtcttgggggtcaccgtggcccagcagcagcaggatggcctgaaaggcagg
cacttgctgagggagatcctggccaacgtctgcctctacctgtgcgccatcatggtgggc
gtcatgtcctactacatggcggaccgcaagcaccgcaaggccttcctggaggcccgccag
tcgctggaggtgaaaatgaacctcgaggagcagagccagcagcaggagaaccttatgctt
tccatcctgcccaagcatgtggctgacgagatgctaaaggacatgaagaaggacgagagc
caaaaggaccagcagcagttcaacaccatgtacatgtatcgccacgagaatgtcagcatc
ctctttgcggacatcgtgggcttcacccagctgtcttccgcctgcagtgcccaggagctc
gtgaagctgctcaacgagctcttcgcccgctttgacaagctggcggccaaataccaccag
ctgcggattaagatcctgggcgactgttactactgcatctgcggcctgcccgactaccgg
gaggaccacgccgtctgctccatccttatggggctcgccatggtggaggccatctcgtac
gtgcgggagaagacgaagactggggtggacatgcgtgtgggggtgcacacaggcacagtg
ctggggggcgtcctgggccagaagcgctggcagtatgacgtgtggtccactgacgtcact
gtggccaacaagatggaggccggtggcatccccgggcgtgtgcacatctcccagagcacc
atggactgcctaaagggcgagttcgatgtggagccgggcgacgggggcagccgctgtgag
tacctggacgagaagggcatcgagacctacctcatcatcgcgtccaagccagaggtgaag
aaaacagccgcccagcacggcctcgacggcccggccctgctgaacggagcgccagcttcc
tcaaagcccagctctcccgccctcattgagaccaaggagcccaacggaagcatccacacc
agcggctccacgtcggaggagcccgaggagcaggatgcccaggcggacaatccctcgttc
cccaacccgcgccggaggctgcgccttcaggacctggctgatcgagtggtggacgcctct
gaggacgagcatgagctcaaccagctactcaatgaggccctgcttgagcgagagtccgcc
caggtagtgaagaagagaaacaccttcctcctttccatgcggttcatggaccccgagatg
gaaacccgctactccgtggagaaggaaaagcagagtggggccgcctttagctgctcctgt
gttgtcctgctctgtacggccctggtcgagatactcatcgacccctggctgatgacaaat
tacatgacctttgtggtcggggaggttctccttctgatcctgacggtctgctcgctggcc
gccatctttccccgggcctttcctaagaagctcgtggccttctcgacttggatcgaccgg
acccgctgggccagaaacacctgggccatgttagccatcttcattctggttatggcaaac
gttgtggacatgcttagctgcctgcagtaccacacaggccccgtcaacagcaccgcaggg
acggaggcagaggatggctgcgtagagaaccccaagtattacagctatgtcgctgtgctg
tccctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacactcatg
ctgcttgtcacgggtgctgtggccgtcatcaacatctacgcctggcgccccatctttgat
gaatatgaccgcaaacgtttccaggaacatgactttcctgcggtcgccttcgagaagatg
caggtactttccacccccgggctcaacggcactgacaggctgcccctggtgccttctaag
tactccatgacagtgatgatcttcatcatgatgctgagcttttactacttctcgcgccac
gtggaaaaattggcacggacactgttcttgtggaagattgaggtccatgaccagaaggaa
cgcgtctacgagatgcggcgctggaatgaggccttggtcaccaacatgttgcctgagcac
gtggcacgccatttcctggggtccaagaaaagagatgaggagctgtacagccagtcttac
gatgagatcggagtcatgtttgcctccctgcccaacttcgccgacttctacacagaggag
agcatcaataatggtggcattgagtgtttgcgcttcctcaacgagatcatctcagatttt
gattctctcctggacaatcctaagttccgggtcatcaccaagatcaaaaccatcggcagc
acctatatggcagcttcaggagtcaccccggatgtcaacaccaatggcttcgccaactcc
aacaaggaggaaaagtctgaccgggagcgctggcagcacctggctgacctggctgacttc
gctctggccatgaaggacacactcaccaacatcaacaaccagtccttcaacaacttcatg
ctgcgcataggcatgaacaaaggaggggtactggctggggtcattggagcccggaaacca
cattatgacatctggggcaatacggtcaacgtagccagcaggatggagtccacaggggtc
atgggtaacattcaggtatgtccagcgagagccgagcatgtgctcagacccagggaccgg
gcacaaagtcagaatagggggtgctttgccacatgctactgcctcctttctgttggccca
ggttatcaagttggtgtttttggaagattaaaggcaagggtggaaagggatgcctcagga
gaagggagggaatacttcgaccccatttccaaaatttag

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