KEGG   Alligator mississippiensis (American alligator): 102567829Help
Entry
102567829         CDS       T03087                                 

Gene name
DOT1L
Definition
(RefSeq) DOT1 like histone lysine methyltransferase
  KO
K11427  histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:2.1.1.43]
Organism
amj  Alligator mississippiensis (American alligator)
Pathway
amj00310  Lysine degradation
Brite
KEGG Orthology (KO) [BR:amj00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    102567829 (DOT1L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:amj03036]
    102567829 (DOT1L)
Enzymes [BR:amj01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     102567829 (DOT1L)
Chromosome and associated proteins [BR:amj03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     102567829 (DOT1L)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DOT1
Motif
Other DBs
NCBI-GeneID: 102567829
NCBI-ProteinID: XP_014455278
UniProt: A0A151NGS8
LinkDB All DBs
Position
Un
AA seq 1546 aa AA seqDB search
MGERLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVH
ENKDSGPEEEKAGANTIKKPSPSKARKKKLSKKGRKMAGRKRGRPKKMNTANTDRKTKKN
QTALELLHAQTVSQTSSSSPQDAYKSPHSPYYQLPPKVQRHSSNQLLVTPTPPALQKLLD
SFKIQYMQFMAYMKTPQYKANLQQLLEQEKEKNVQLLGTAQQLFTHCQAQKEEIKRLFQQ
KLDELGVKALTYNDLIQAQKEISAHNQQLKEQTKQLEKDNSELRNQSLQLLKARCEELKL
DWSTLSLENLLKEKQALKNQISEKQKHCLELQISIVELEKSQRQQELMQLKSYTPSDESL
SIQLRNKNHLSREPEVDHGRFQLELECSKFPMTHINGMSPELSMNGHATPYEIHNTLSRP
SSKQNTPQYMTSHLDQEIVPCTPNHSSRQKADKTSSLSLPDYTRFSPAKIALRRHLNQDH
AVNGKATTNEIQRADHIKENGLTYPSPNISNGMKLSPQETRPSSPAALPIAGEKVLRERT
SASNGETITSLPISIPLSTVQPNKLPVSIPLASVVLPSRVEKVRSTPSPVHQNRDSSTLE
KQIGASSHNGISNAAGNKPLALATSGFSYSSGSVAVNGTLSNSPAQLNHSVDQAALDDSG
SLFNSVGSRSSTPQHPLLMMQSRNSGQNSPAHQHSTSPRLNGASQSLVGVLQYADAQKMF
AEGTKGDLQSDAAFSDPENEAKRRIIFTISPNTGNVKQSPSNKHSPLTSSIRLDCGQAYM
QDGKKRGRRKRSSTGNLSVSSGVSPKRKSLPTVAGLFTQPSGSPLNINSMVNNINQPLEI
TAISSPENSLKNSPVPYQDNDQPPVLKKEKPLIQTNGIHYSPLTSDEEQGSEDEHNSTRI
ERKIATISLESKSPQKTVENGGSLAGRKQAQTSENMNSSKWKSTFSPISDINLTKTTDSP
LQAVSSLSQNSLFAFRPSSEDGMAIDSKITAHARKNVTMPSSGTDGLSPNTNAANGFTYN
GGLTTDIGLHSFIDGASLPHKISDVTSLNSSLSFQSQRSKDLGVSETNPFLNKRQLEGLG
SMKGEDLNRSGVKSKEMSELNIRTGGSSEKSSLQHNGKASKGRDRDVEFKNGHNLFISAA
AVSSGGLLNGKSLSTAVSSAGNPASVQTHHSFLNTLTTGSQFPLGPMALPANLNSVTNSS
VLQSLFNTMPAAASLVHVSSAATRLTNSHTMGNFSSGVTGGTVGGN
NT seq 4641 nt NT seq  +upstreamnt  +downstreamnt
atgggcgagaggctggagctccggctgaagtcgcccgtgggcgccgagccggccgtctac
ccctggccgctgcccgtctacgacaaacaccatgatgctgctcatgaaatcattgagaca
attcggtgggtctgtgaagaaatcccagatctcaagcttgctatggaaaattatgtttta
attgactatgatacaaaaagctttgaaagcatgcagaggctttgtgacaaatacaaccga
gccattgatagcattcatcagttgtggaaaggaaccacccagcccatgaaactgaacact
cgtccttccaatggactcctccgtcatatcctgcagcaagtatataaccactcggtgacc
gacccagagaaactcaacaactatgaacccttttccccagaggtgtatggagaaacttcc
tttgatttagtggcccaaatgattgatgaaattaagatgacagaggatgacttgtttgtc
gatttgggcagtggtgtgggtcaggtggtgctccaagttgctgcagccacaaactgcaaa
catcactatggtgtggagaaagctgatattccagccaaatatgctgagacgatggacaga
gagttcagaaagtggatgaaatggtatgggaaaaaacatgcagaatacacactggaaaga
ggtgacttcctctcagaagaatggagagagcgaattgcaaacacaagtgttatttttgtg
aataattttgcctttggtcctgaggtggatcaccaactgaaggagcgatttgcgaacatg
aaggaaggtggcagaatcgtgtcctcaaaaccttttgcacctctgaattttagaataaat
agtcgaaacttgagtgatattggcactataatgagagttgtggaattatcaccactgaaa
gggtctgtttcatggacagggaaaccagtttcctactacctgcatactattgatcgaacc
atacttgaaaactatttttctagtctcaaaaatccaaaactcagggaggaacaagaggca
gctagacgtcgtcagcaaagagaaaacaagagcaacacaacaactccgacaaaggtgcac
gaaaacaaggattctggtcctgaagaggaaaaagctggggcaaacaccattaagaagcca
tctccctccaaagcacgcaagaagaagctgagtaaaaaaggaaggaaaatggcaggcagg
aaacgagggcgtcctaagaagatgaacactgcaaatacggaccgcaagaccaagaagaac
caaactgcactggagcttctgcatgctcaaactgtgtcacagacatcctcatcctctcct
caggatgcatacaagtcacctcatagtccatattaccaactacctccgaaggtgcaacgg
cattcatctaaccagctgttggtgactcccaccccacctgcactacagaagctgctagac
tcttttaagatccaatacatgcagttcatggcgtacatgaaaactcctcagtacaaagca
aacctgcaacagttattggagcaggaaaaggaaaagaacgttcagttattggggacagcg
cagcagttgttcacccattgccaggcccaaaaagaggaaatcaagcgactgtttcaacaa
aagctcgatgagttgggagttaaggctctgacatataatgacctgattcaggctcagaag
gagatctctgctcacaaccagcagctgaaagaacagacgaagcagctggagaaagataac
agtgaactcaggaaccagagcttgcagctgcttaaggcacggtgtgaagaactgaaattg
gactggtcaactctttcacttgagaacttactgaaggaaaaacaggcgctgaagaatcag
atttcggagaaacaaaagcactgcttggaattgcagatcagcattgtggagcttgagaaa
agtcaaaggcagcaggagctcatgcagctgaaatcctatacgccgtccgatgagtccttg
tcaatacaactacgcaataaaaatcatctaagtcgtgaacctgaggttgatcatggcagg
ttccaacttgagcttgagtgttctaaatttcctatgacccatatcaatggcatgagtccc
gaactgtccatgaatggccatgctactccctatgaaatccataatactcttagccggccc
tcttccaagcaaaacacccctcagtatatgacctctcacctggaccaagaaatagttcca
tgtaccccaaaccacagcagtagacagaaggcggacaagacatccagcttgtccttacct
gattataccagattttcccctgctaagatagccctaaggaggcacttgaatcaggaccat
gcagtcaatggaaaagcaacaactaatgaaattcagagagctgaccacataaaagagaat
ggccttacatatccaagccctaatatttcaaatggcatgaagctgagtcctcaggaaact
cggccctcttccccagcggccttaccgattgcaggcgagaaggttttaagagagagaacc
tctgcaagtaatggagaaactatcaccagcctacctatcagtattcctctcagcacagtg
cagcccaataaactccctgttagtatccctctggccagcgtagtcctacctagccgtgtt
gagaaggtgagaagcacaccaagtccagttcatcagaatagagactcatcaacacttgaa
aagcagattggtgctagttctcataatggcataagcaatgctgctggaaacaagccactg
gctttggctacctcaggtttttcttattcttctggctccgtggcagtcaatggaactctt
tcaaacagcccagcccaacttaaccatagtgttgatcaggcagctctggacgactctggg
agtctgtttaactcggtagggtctcgcagttccactccacaacaccctttgctaatgatg
cagtcacggaactcggggcaaaactcccctgctcaccagcactcaacaagccccaggtta
aacggagcctcccagagcctggtaggggtattgcagtatgcagatgctcagaagatgttt
gctgaaggaacaaagggggatcttcagtctgatgcagcattttcagatcccgagaacgag
gccaagagaagaatcatctttacaatctctcctaatacaggaaatgtaaaacaatctcct
tccaacaagcacagtcccctgacctcgagcattcggctggactgtggtcaagcatacatg
caagatgggaagaaacgaggtcgaaggaagagatcttctactgggaatctcagcgtgagc
tctggggtgtcccccaaacgcaaatccttaccaacagtggctggactgtttactcagcct
tcagggtcaccactcaatattaactccatggtcaataacattaatcagcctttagaaata
acagccatttcctcccctgaaaactccctgaagaactctcctgttccctaccaggacaat
gaccagcccccagtgctgaaaaaggagaagcccctcattcagaccaatggcattcattac
tcgccgctgacatctgatgaagagcaggggtctgaagatgagcacaatagtaccagaatt
gagagaaaaattgcaacaatatcattggaaagcaaatctccacaaaagactgttgaaaat
ggtggcagtttagctggaagaaaacaagcgcaaaccagcgagaacatgaatagcagtaaa
tggaagtctaccttttcaccaatatctgacatcaacctgaccaaaactacagatagtccc
ttgcaggctgtttcatctctgagccagaattcactgtttgccttcaggccatcctctgag
gatggcatggccattgacagcaagatcacggcacatgcgagaaaaaatgtcaccatgccc
tcctctggaacagatggactcagccccaacacaaatgctgcaaatggattcacgtacaac
ggtggactgacgacagatattggtttacacagctttattgatggtgcttctcttcctcat
aagatttcagatgtgacttcccttaattcctctctgagttttcagtctcagcggagcaaa
gacttgggtgtctcagagacaaatccctttttgaacaagaggcagcttgaaggcctaggc
agcatgaaaggggaagacttaaatcggtcaggggtcaaaagcaaagagatgagcgaatta
aacattcgtacagggggctcttcagaaaaaagctctttgcagcataatggaaaggccagc
aaaggacgggaccgagatgtggagtttaaaaatggccacaaccttttcatttctgctgct
gctgtatcttcgggtggccttctaaatggcaaaagcctttccactgctgtttcctcagca
ggcaacccagcatctgttcagacacaccattctttcttaaacactttgaccactggatcg
cagttcccccttggccccatggccttgccagcaaacctcaactcggtgacgaactcttca
gtattgcagtctttatttaatacaatgccagctgctgccagtctggtccacgtgtcatca
gctgcaaccagactgactaattctcacactatggggaacttctcttctggggttacaggt
ggaacagttggaggtaactag

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