KEGG T01329: 100464991

KEGG Orthology (KO) [BR:aml00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100464991 (PDGFRA)
   04014 Ras signaling pathway
    100464991 (PDGFRA)
   04015 Rap1 signaling pathway
    100464991 (PDGFRA)
   04630 JAK-STAT signaling pathway
    100464991 (PDGFRA)
   04020 Calcium signaling pathway
    100464991 (PDGFRA)
   04072 Phospholipase D signaling pathway
    100464991 (PDGFRA)
   04151 PI3K-Akt signaling pathway
    100464991 (PDGFRA)
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100464991 (PDGFRA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100464991 (PDGFRA)
   04540 Gap junction
    100464991 (PDGFRA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100464991 (PDGFRA)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100464991 (PDGFRA)
   05206 MicroRNAs in cancer
    100464991 (PDGFRA)
   05230 Central carbon metabolism in cancer
    100464991 (PDGFRA)
   05231 Choline metabolism in cancer
    100464991 (PDGFRA)
  09162 Cancer: specific types
   05214 Glioma
    100464991 (PDGFRA)
   05218 Melanoma
    100464991 (PDGFRA)
   05215 Prostate cancer
    100464991 (PDGFRA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    100464991 (PDGFRA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100464991 (PDGFRA)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aml01001]
    100464991 (PDGFRA)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:aml04090]
    100464991 (PDGFRA)
Enzymes [BR:aml01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100464991 (PDGFRA)
Protein kinases [BR:aml01001]
Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   100464991 (PDGFRA)
CD molecules [BR:aml04090]
Proteins
  100464991 (PDGFRA)

SSDB

Motif

Pfam:

PK_Tyr_Ser-Thr Pkinase Ig_3 I-set ig Ig_2 V-set Herpes_gE Kinase-like LAT

Other DBs

NCBI-GeneID:

100464991

NCBI-ProteinID:

XP_002919416

Ensembl:

ENSAMEG00000018351

LinkDB

Position

AA seq 1090 aa
MMRTSLLGFLILGCLLTGPSRIFCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQY
PMSEEENPNVEIRNEENNSGLFVAVLEVVNASAAHTGLYTCYYNHTQTEETDVEGRRIYI
YVPDPDVAFVPLGMTDYLVIVENDDSAIIPCRTTDPKTPVTLRSNDRVVHASYDSRQGFN
GTFSVGPYICEATVRGKKFQTIPFNIYSLKATSELDLEMEALKTVYKSGETIVVTCAVFN
NEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLRVPEATVKDSGDYECAARQATKEV
KEMKKVTISVYEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIEN
LTEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILD
LVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWVILASNISNIITEVHPR
DRNTVEGRVTFTRVEETIAVRCLAKNLLGAQSRELKLVAPTLRSELTVAAAVLVLLVIVI
ISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRIL
GSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVN
LLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADDSTRS
YVILSFENNGDYMDMKQADATQYVPMLERKEAAKYSDVQRSLYDRPASSKKKSVLDSEVK
NLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGL
ARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGM
MVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYK
KSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYI
IPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGID
SSDLVEDSFL

NT seq 3273 nt +upstreamnt +downstreamnt
atgatgaggacttcccttctgggcttcctgatcttaggctgtctcctcacagggcccagc
cgaatcttctgccagctttcattaccctccatcctgccaaacgaaaatgaaaaggtcgtg
cagctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtac
cccatgtctgaagaagagaaccccaatgtggaaatcagaaacgaggagaacaacagtggc
ctttttgtggccgtgctggaagtggtcaacgcgtcggcggcacacacgggcttgtacact
tgctattacaaccacacgcagacggaggagaccgacgtcgagggccggcgtatctacatc
tatgtgccagacccggatgtagcctttgtgcctctgggaatgacagattatttagtcatc
gtggagaatgatgattctgccatcataccatgtcgcacgactgatcccaagactccggtc
accttgcgcagcaatgacagggtggtgcacgcctcctatgacagcagacagggcttcaat
gggaccttcagcgttgggccctatatctgtgaagccaccgtcaggggaaagaagttccag
accatcccatttaatatttattctttaaaagcaacgtcagaacttgatctagaaatggaa
gctcttaaaactgtgtataagtcaggggagacgattgtggtcacctgcgccgtctttaac
aacgaggtggtcgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcacc
atgctggaggaaatcaaggtcccgtccatcaaattggtgtatactctgagggtccctgag
gccacggtgaaagatagtggagattatgagtgtgctgcccgccaggccaccaaggaggtc
aaagagatgaagaaagtcaccatttctgtctatgagaaagggttcattgaaatcaaaccc
aacttcagcccattggaagctgtcgacctgcatgaagtcaaacatttcgtggtggatgtg
caggcctacccccctcccaggatatcctggctgaaggacaacctgactctgattgaaaat
ctcacggagatcaccacggacatagaaaagattcaggaaataaggtatcggagcaaatta
aagctgatccgtgctaaggaggaagacagtggccattacacgattgtcgttcaaaatgaa
gatgacgtgaagagctacactttcgaactcttaacgcaagttccctcatctattctggac
ttggtggacgaccaccacggctccacggggggacagaccgtgagatgcaccgctgaaggg
acacctcttcctgatatcgagtggatgatttgcaaggatattaagaagtgtaataatgaa
acttcatgggtgattttggccagcaatatctcaaacatcatcacggaggtccacccccga
gacaggaacactgtggagggccgagtgacgttcaccagagtggaggagaccatcgccgtt
cgatgtctggccaagaatctccttggggcccagagccgcgagctcaagctggtggccccc
acgctgcgctctgagctcactgtggccgctgccgtcctcgtgctgctggtgattgtgatc
atctcccttatcgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgctgg
agggtcattgaatccatcagcccggatggacatgaatatatttatgtggacccaatgcag
ctgccttatgactcgagatgggagtttccaagagatggactagtgcttggtcgtatcctg
ggatctggcgcgtttgggaaagtggttgaaggaactgcctatggattaagccgctcccag
cctgtcatgaaggtagcagtgaagatgctgaaacccacagccagatccagtgagaaacag
gctcttatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtgaac
ttgctgggagcctgtaccaagtcaggccctatttacatcatcactgagtactgcttctat
ggggatttggtcaactatttgcataagaatcgggatagcttcctgagccgccacccagag
aagccaaagaaagagctggacatttttggattgaaccctgccgacgacagcacacggagt
tacgtcattttatcttttgaaaacaatggtgactacatggacatgaagcaagctgacgcc
acccagtacgtccccatgctggaaaggaaagaggctgccaagtactcggacgtccagagg
tcgctgtatgatcgcccggcctcgtctaagaagaagtctgtgttagactcagaagtcaaa
aacctcctttcggatgataactcagaaggccttactttgttggatttgttgagctttacc
tatcaagttgcgcgaggaatggaatttttggcttcgaaaaattgtgtccaccgggacctg
gctgctcgaaacgtcctcctggcgcaagggaaaatcgtgaagatctgtgacttcggcctg
gccagagatatcatgcacgattcgaactacgtgtcaaaaggcagtacctttctccccgtg
aagtggatggcccctgagagcatcttcgacaacctctacaccacactgagtgacgtctgg
tcttacggcattctgctctgggagatcttttccctcggcggcacaccctaccccggcatg
atggtggattctactttctacaataagattaagagtgggtaccggatggccaagcctgac
cacgccaccagtgaagtctacgagatcatggtgaaatgctggcacagtgagccggagaag
agaccctccttctaccacctgagtgagattgtggagaatctgctgcccggacagtataag
aagagttacgaaaagattcacctggacttcctgaagagcgaccaccccgccgtggcgcgc
atgcgcgtggactcagacaacgcctacattggcgttacctacaaaaacgaggaagacaag
ctgaaggactgggagggcagcctggacgagcagaggctgagtgcggacagcggctacatc
atccccctgcccgacatcgaccctgtccctgaggaggaggacctgggcaagaggaacaga
cacagctcgcagacctccgaagagagcgctatcgagacaggttcgagtagctccaccttc
atcaagagagaggacgagaccatcgaggacatcgacatgatggatgacattggcatagac
tcctcagacctggtagaggacagtttcctgtga

Ailuropoda melanoleuca (giant panda): 100472005

Entry

100472005 CDS T01329

Gene name

PDGFRB

Definition

(RefSeq) LOW QUALITY PROTEIN: platelet-derived growth factor receptor beta

K05089

platelet-derived growth factor receptor beta [EC:2.7.10.1]

Organism

aml Ailuropoda melanoleuca (giant panda)

Pathway

aml01521

EGFR tyrosine kinase inhibitor resistance

aml04010

MAPK signaling pathway

aml04014

Ras signaling pathway

aml04015

Rap1 signaling pathway

aml04020

Calcium signaling pathway

aml04072

Phospholipase D signaling pathway

aml04151

PI3K-Akt signaling pathway

aml04510

Focal adhesion

aml04540

Gap junction

aml04630

JAK-STAT signaling pathway

aml04810

Regulation of actin cytoskeleton

aml05165

Human papillomavirus infection

aml05200

Pathways in cancer

aml05206

MicroRNAs in cancer

aml05214

Glioma

aml05215

Prostate cancer

aml05218

Melanoma

aml05230

Central carbon metabolism in cancer

aml05231

Choline metabolism in cancer

Brite

KEGG Orthology (KO) [BR:aml00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100472005 (PDGFRB)
   04014 Ras signaling pathway
    100472005 (PDGFRB)
   04015 Rap1 signaling pathway
    100472005 (PDGFRB)
   04630 JAK-STAT signaling pathway
    100472005 (PDGFRB)
   04020 Calcium signaling pathway
    100472005 (PDGFRB)
   04072 Phospholipase D signaling pathway
    100472005 (PDGFRB)
   04151 PI3K-Akt signaling pathway
    100472005 (PDGFRB)
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100472005 (PDGFRB)
   04540 Gap junction
    100472005 (PDGFRB)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100472005 (PDGFRB)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100472005 (PDGFRB)
   05206 MicroRNAs in cancer
    100472005 (PDGFRB)
   05230 Central carbon metabolism in cancer
    100472005 (PDGFRB)
   05231 Choline metabolism in cancer
    100472005 (PDGFRB)
  09162 Cancer: specific types
   05214 Glioma
    100472005 (PDGFRB)
   05218 Melanoma
    100472005 (PDGFRB)
   05215 Prostate cancer
    100472005 (PDGFRB)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    100472005 (PDGFRB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100472005 (PDGFRB)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aml01001]
    100472005 (PDGFRB)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:aml04090]
    100472005 (PDGFRB)
Enzymes [BR:aml01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100472005 (PDGFRB)
Protein kinases [BR:aml01001]
Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   100472005 (PDGFRB)
CD molecules [BR:aml04090]
Proteins
  100472005 (PDGFRB)

SSDB

Motif

Pfam:

PK_Tyr_Ser-Thr Pkinase Ig_3 ig I-set Ig_2 V-set C2-set_2 Ig_6 TrmE_N

Other DBs

NCBI-GeneID:

100472005

NCBI-ProteinID:

XP_034512770

Ensembl:

ENSAMEG00000004961

LinkDB

Position

AA seq 1111 aa
MSERSCSYKDTMQLPSAMPAPVLKGQVLLLPLLLLLGPQASWGLVITPPGPELILNVSSN
FVLTCSGPAPVVWERMSQEPLQKMAKTQDGTFSSTLTLTNVSGIDTGEYFCTYKGSHGLE
PGERKRLYIFVPDPSMGFLPVDPEELFIFLTEITEITIPCRVSDPRLVVTLHEKKVDIPL
PIPYDHQRGFSGTFEDKTYVCKTTIGDKEVDSEAYYVYSLQVSSINVSVNAVQTVVRQGE
NITIMCIVTGNEVVNFEWTYPRMESGRLVEPVTDFLFNMPSHIRSILHIPSAELGDSGTY
ICNVSESVNEHRDEKSINVTVVESGYVRLLGELDAIQFAELHRSRTLQVMFEAYPPPTVM
WFKDNRTLGDSSAGEISLSTRNVSETRYVSELTLVRVKVAEAGCYTMRAFHEDAEAQLSF
QLQVNVPVRVLELSESHPASGEQTVRCRGRGMPQPHLTWSTCSDLKRCPRELPPTPLGNS
SEEESQLETNVTYWPEEQEFEVVSTLRLRRVDQPLSVRCTLHNLLGHDMQEVTVVPHSLP
FKVVVISAILALVVLTVISLIILVMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPY
DSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALM
SELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQRCPDKRR
PPSAELYSNALPGGLPLPSHVSLPGESDGGYMDMSKDESVDYVPMLAMKGGVKYADIESS
SYMAPYDNYVPTAPERTCRATLINESPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAA
RNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSF
GILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRP
PFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAVLRSQARLPGFHGLRSPLDTSSVLY
TAVQPNEGDNDYIIPLPDPKPEVADEGPLESSPSLASSTLNEVNTPSTISCDSPLEPQEE
PEPQPEPQGEPEPPLESSCPGLRAEAEDSFL

NT seq 3336 nt +upstreamnt +downstreamnt
atgtcagagaggtcatgcagttacaaggacaccatgcagcttccgagcgccatgccagct
cctgtcctcaaaggccaggtgctactgctgcccctgctgttgctgctgggcccacaggcc
tcctggggcctggtcatcacacccccggggccagagcttatcctcaatgtctccagcaac
ttcgtgctgacctgctcaggtccagctccggtggtgtgggaacggatgtcccaggagccc
ctgcagaaaatggccaagacccaggatggcaccttctccagcacactgacactgaccaat
gtctctgggatagacacgggagaatacttctgcacctacaaaggctcccatgggctggag
cctggggagcggaaacggctctacatctttgtgccagatccctcgatgggctttctccca
gtcgaccccgaggaactattcatcttcctcacggaaataactgagatcacaattccatgc
cgagtgtcggatccgagactggtggtgacactgcacgagaagaaagtggatatcccactg
cccatcccctatgaccaccaacgtggcttctctggtaccttcgaggacaagacctatgtc
tgtaaaaccaccatcggggacaaggaagttgattctgaagcctactatgtctacagcctc
caggtgtcatccatcaatgtctcagtgaatgcagtgcagactgtggtccgtcagggtgag
aatatcaccatcatgtgcattgtgactggaaatgaggtggtcaactttgaatggacatac
ccacgcatggagagcgggcggctggtggagccagtgactgacttcctcttcaatatgccc
tcccacatacgctccatcctgcacatccccagtgctgagcttggcgattcagggacctac
atctgcaatgtatcagagagtgtgaatgagcatcgagatgaaaagtccatcaatgtcact
gtggttgagagtggctacgtgcggctgctgggagagctggacgccatacaattcgcggag
ctgcaccgcagcaggactctgcaggtcatgttcgaggcctacccgccgcctactgtcatg
tggttcaaggacaaccgcacgctaggcgactccagcgcaggcgagatctccctgtccaca
cgcaatgtgtctgagacccggtacgtgtcagaactgacgttggtacgggtgaaggtggcc
gaggcgggctgctacaccatgcgggccttccatgaggacgcggaggcccagctctccttc
cagctgcaggtcaacgtgcctgtccgtgtactggagctgagtgaaagccaccctgccagc
ggggagcagacagtccgctgtcgtggcaggggcatgccccagccacacctcacctggtct
acctgcagcgacctcaaaagatgtccgcgcgagctgccgcccacgccgctggggaacagt
tcggaggaggagagccagctggagactaacgtgacgtactggcccgaggagcaggagttc
gaggtggtgagcacgctgcgcctgcgccgtgtcgatcagccgctgtccgtgcgctgcact
ctgcacaacctgctgggacacgacatgcaggaggtcaccgtggtgccgcattctctgccc
ttcaaggtggtggtgatctcagccatcctggccttggtggtcctcacagtcatctccctc
atcatcctcgtcatgctctggcagaagaagccacgttacgagatccgatggaaggtgatt
gaatccgtgagctccgacggccatgagtacatctacgtggatcctatgcagctgccctac
gactccacctgggagctgccgcgggaccagctcgtgcttggacgcaccctcggctctggg
gcctttggccaggtggtggaggccacggctcatggcctgagccattcgcaggccacgatg
aaagtggcagtcaagatgctgaaatccacagcccgcagcagtgagaagcaggccctcatg
tctgagctgaagatcatgagtcacctcgggccccatctgaacgtggtcaacttgctgggg
gcctgcaccaaaggaggacccatctacatcatcaccgagtactgccgctacggcgacctg
gttgactacctgcaccgcaacaagcacaccttcctgcagcgctgccccgacaagcgccgc
ccgcccagcgccgagctctacagcaacgcgctgcccggcgggctcccgctgcccagccac
gtgtctctgcccggggagagcgacggcggctacatggacatgagcaaggacgagtccgtg
gactacgtgcccatgctggccatgaaaggaggcgtcaaatacgcagacatcgagtcctcc
agctacatggccccttatgacaactacgtccccaccgctcctgagaggacctgtcgggca
actctgatcaacgagtccccagtgcttagctacacggatctcgtgggcttcagctaccag
gtggccaacggcatggagttcctggcctccaagaactgtgtccaccgagatctggcagcc
agaaatgtgctcatctgtgagggcaagctggtcaagatctgtgactttggcctggctcgt
gacatcatgcgagactcaaactatatctccaaaggcagcaccttcctgcctctgaagtgg
atggctcctgagagcatcttcaacagcctctataccaccctgagcgacgtgtggtccttc
gggatcctcctctgggagatcttcaccctgggtggcaccccttacccagagctgcccatg
aacgaccagttctataacgccatcaagcgagggtaccgcatggcccagcctgcccacgcc
tccgacgagatttacgagatcatgcagaagtgctgggaagagaaattcgagatccggcct
cctttctcgcagctggtgctgctccttgagaggctgctgggcgagggatacaaaaagaag
taccagcaggtggatgaggagtttctgaggagcgaccacccagccgtccttcggtcccaa
gcccgcttgcctggcttccatggcctccgatcccccctggacaccagctctgtcctctac
actgctgtgcagcccaacgagggtgacaacgactacatcatccccctgcctgaccccaaa
cctgaggttgctgatgagggcccactggagagttctcccagccttgccagctccaccctg
aatgaagtcaacaccccctctaccatctcctgcgacagccccctggagccccaagaggag
ccagagccccagcccgagccccagggggagccggagccgccactggagtcaagctgccct
gggcttcgggccgaggcggaggacagcttcctgtag

DBGET integrated database retrieval system