Ailuropoda melanoleuca (giant panda): 100468916
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Entry
100468916 CDS
T01329
Gene name
GRB2
Definition
(RefSeq) growth factor receptor-bound protein 2 isoform X1
KO
K04364
growth factor receptor-bound protein 2
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml01521
EGFR tyrosine kinase inhibitor resistance
aml01522
Endocrine resistance
aml04010
MAPK signaling pathway
aml04012
ErbB signaling pathway
aml04014
Ras signaling pathway
aml04062
Chemokine signaling pathway
aml04068
FoxO signaling pathway
aml04072
Phospholipase D signaling pathway
aml04150
mTOR signaling pathway
aml04151
PI3K-Akt signaling pathway
aml04380
Osteoclast differentiation
aml04510
Focal adhesion
aml04540
Gap junction
aml04550
Signaling pathways regulating pluripotency of stem cells
aml04630
JAK-STAT signaling pathway
aml04650
Natural killer cell mediated cytotoxicity
aml04660
T cell receptor signaling pathway
aml04662
B cell receptor signaling pathway
aml04664
Fc epsilon RI signaling pathway
aml04714
Thermogenesis
aml04722
Neurotrophin signaling pathway
aml04910
Insulin signaling pathway
aml04912
GnRH signaling pathway
aml04915
Estrogen signaling pathway
aml04917
Prolactin signaling pathway
aml04926
Relaxin signaling pathway
aml04935
Growth hormone synthesis, secretion and action
aml05034
Alcoholism
aml05160
Hepatitis C
aml05161
Hepatitis B
aml05163
Human cytomegalovirus infection
aml05165
Human papillomavirus infection
aml05200
Pathways in cancer
aml05203
Viral carcinogenesis
aml05205
Proteoglycans in cancer
aml05206
MicroRNAs in cancer
aml05210
Colorectal cancer
aml05211
Renal cell carcinoma
aml05213
Endometrial cancer
aml05214
Glioma
aml05215
Prostate cancer
aml05220
Chronic myeloid leukemia
aml05221
Acute myeloid leukemia
aml05223
Non-small cell lung cancer
aml05224
Breast cancer
aml05225
Hepatocellular carcinoma
aml05226
Gastric cancer
aml05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100468916 (GRB2)
04012 ErbB signaling pathway
100468916 (GRB2)
04014 Ras signaling pathway
100468916 (GRB2)
04630 JAK-STAT signaling pathway
100468916 (GRB2)
04068 FoxO signaling pathway
100468916 (GRB2)
04072 Phospholipase D signaling pathway
100468916 (GRB2)
04151 PI3K-Akt signaling pathway
100468916 (GRB2)
04150 mTOR signaling pathway
100468916 (GRB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100468916 (GRB2)
04540 Gap junction
100468916 (GRB2)
04550 Signaling pathways regulating pluripotency of stem cells
100468916 (GRB2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100468916 (GRB2)
04660 T cell receptor signaling pathway
100468916 (GRB2)
04662 B cell receptor signaling pathway
100468916 (GRB2)
04664 Fc epsilon RI signaling pathway
100468916 (GRB2)
04062 Chemokine signaling pathway
100468916 (GRB2)
09152 Endocrine system
04910 Insulin signaling pathway
100468916 (GRB2)
04912 GnRH signaling pathway
100468916 (GRB2)
04915 Estrogen signaling pathway
100468916 (GRB2)
04917 Prolactin signaling pathway
100468916 (GRB2)
04926 Relaxin signaling pathway
100468916 (GRB2)
04935 Growth hormone synthesis, secretion and action
100468916 (GRB2)
09156 Nervous system
04722 Neurotrophin signaling pathway
100468916 (GRB2)
09158 Development and regeneration
04380 Osteoclast differentiation
100468916 (GRB2)
09159 Environmental adaptation
04714 Thermogenesis
100468916 (GRB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100468916 (GRB2)
05206 MicroRNAs in cancer
100468916 (GRB2)
05205 Proteoglycans in cancer
100468916 (GRB2)
05203 Viral carcinogenesis
100468916 (GRB2)
05231 Choline metabolism in cancer
100468916 (GRB2)
09162 Cancer: specific types
05210 Colorectal cancer
100468916 (GRB2)
05225 Hepatocellular carcinoma
100468916 (GRB2)
05226 Gastric cancer
100468916 (GRB2)
05214 Glioma
100468916 (GRB2)
05221 Acute myeloid leukemia
100468916 (GRB2)
05220 Chronic myeloid leukemia
100468916 (GRB2)
05211 Renal cell carcinoma
100468916 (GRB2)
05215 Prostate cancer
100468916 (GRB2)
05213 Endometrial cancer
100468916 (GRB2)
05224 Breast cancer
100468916 (GRB2)
05223 Non-small cell lung cancer
100468916 (GRB2)
09165 Substance dependence
05034 Alcoholism
100468916 (GRB2)
09172 Infectious disease: viral
05161 Hepatitis B
100468916 (GRB2)
05160 Hepatitis C
100468916 (GRB2)
05163 Human cytomegalovirus infection
100468916 (GRB2)
05165 Human papillomavirus infection
100468916 (GRB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100468916 (GRB2)
01522 Endocrine resistance
100468916 (GRB2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
aml04131
]
100468916 (GRB2)
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:
aml04990
]
100468916 (GRB2)
Membrane trafficking [BR:
aml04131
]
Endocytosis
Clathrin-mediated endocytosis
Receptor tyrosine kinase (RTK) adaptor proteins
100468916 (GRB2)
Domain-containing proteins not elsewhere classified [BR:
aml04990
]
Src homology (SH) domain-containing proteins
Signal transducing adaptor proteins
100468916 (GRB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SH3_1
SH3_9
SH3_2
SH2
SH3_10
SH2_2
SH3_3
DUF5093
hSH3
SH3_4
Motif
Other DBs
NCBI-GeneID:
100468916
NCBI-ProteinID:
XP_019655876
Ensembl:
ENSAMEG00000009339
UniProt:
D2HD44
LinkDB
All DBs
Position
13
AA seq
217 aa
AA seq
DB search
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq
654 nt
NT seq
+upstream
nt +downstream
nt
atggaagccatcgccaaatatgacttcaaagctactgctgacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagaa
ctcaatgggaaagatggcttcattcccaagaattatatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcatgac
ggggcctttcttatccgagagagtgagagtgcccctggggacttctccctctctgtcaag
tttggaaatgatgtacagcacttcaaggtgctccgagatggagctgggaagtatttcctc
tgggtggtgaaattcaattctctgaacgagctggtagattatcacaggtctacatccgtc
tccagaaaccagcagatattcctccgggacatagaacaggtgccacagcaaccaacgtac
gtccaggccctctttgactttgatccccaggaggatggagagctgggattccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcctgccacggg
cagaccggcatgtttccccgcaattacgtcacccccgtgaaccggaacgtctaa
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