KEGG   Ailuropoda melanoleuca (giant panda): 100469938
Entry
100469938         CDS       T01329                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml01521  EGFR tyrosine kinase inhibitor resistance
aml04062  Chemokine signaling pathway
aml04066  HIF-1 signaling pathway
aml04068  FoxO signaling pathway
aml04217  Necroptosis
aml04550  Signaling pathways regulating pluripotency of stem cells
aml04630  JAK-STAT signaling pathway
aml04659  Th17 cell differentiation
aml04917  Prolactin signaling pathway
aml04920  Adipocytokine signaling pathway
aml04931  Insulin resistance
aml04933  AGE-RAGE signaling pathway in diabetic complications
aml04935  Growth hormone synthesis, secretion and action
aml05145  Toxoplasmosis
aml05160  Hepatitis C
aml05161  Hepatitis B
aml05162  Measles
aml05163  Human cytomegalovirus infection
aml05167  Kaposi sarcoma-associated herpesvirus infection
aml05169  Epstein-Barr virus infection
aml05200  Pathways in cancer
aml05203  Viral carcinogenesis
aml05205  Proteoglycans in cancer
aml05206  MicroRNAs in cancer
aml05212  Pancreatic cancer
aml05221  Acute myeloid leukemia
aml05223  Non-small cell lung cancer
aml05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
aml05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100469938 (STAT3)
   04066 HIF-1 signaling pathway
    100469938 (STAT3)
   04068 FoxO signaling pathway
    100469938 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100469938 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100469938 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100469938 (STAT3)
   04062 Chemokine signaling pathway
    100469938 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    100469938 (STAT3)
   04917 Prolactin signaling pathway
    100469938 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    100469938 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100469938 (STAT3)
   05206 MicroRNAs in cancer
    100469938 (STAT3)
   05205 Proteoglycans in cancer
    100469938 (STAT3)
   05203 Viral carcinogenesis
    100469938 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100469938 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100469938 (STAT3)
   05221 Acute myeloid leukemia
    100469938 (STAT3)
   05223 Non-small cell lung cancer
    100469938 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100469938 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100469938 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100469938 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    100469938 (STAT3)
   05161 Hepatitis B
    100469938 (STAT3)
   05160 Hepatitis C
    100469938 (STAT3)
   05163 Human cytomegalovirus infection
    100469938 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100469938 (STAT3)
   05169 Epstein-Barr virus infection
    100469938 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100469938 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100469938 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:aml03000]
    100469938 (STAT3)
Transcription factors [BR:aml03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    100469938 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Fib_alpha
Other DBs
NCBI-GeneID: 100469938
NCBI-ProteinID: XP_034497574
Ensembl: ENSAMEG00000006266
LinkDB
Position
13
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctccagcagctcgacacacggtacctggagcagcttcatcag
ctgtacagtgacagcttcccgatggagctgcggcagtttctggccccttggattgagagt
caagattgggcatatgcggccagcaaagaatcacatgcgactttggtgtttcataatctc
ttgggtgagattgaccagcagtacagccgcttcctacaggagtcaaatgttctctatcag
cacaatctgcgaaggatcaagcagttccttcagagcagatatctggagaagccaatggag
attgcccgaatcgtggcccggtgcctgtgggaagagtcccgcctgctccagactgcagcc
actgcagcccagcaagggggccaggccaaccaccccacagccgccgtggtgacggagaag
cagcagatgctggagcagcacctccaggatgttcggaagcgagtacaggatctagaacag
aaaatgaaagtggtggagaatctccaggatgactttgatttcaactacaaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtcggtgacccggcagaagatg
cagcagctggagcagatgctcaccgcgctggaccagatgcggcgcagcatcgtgagtgag
ttggcggggctgttgtccgcgatggagtatgtgcagaaaactctcacggacgaagagctg
gctgactggaagaggcggcagcagattgcgtgcatcgggggccctcccaacatctgccta
gatcgcctagaaaattggataacctcattagcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagttgcagcaaaaagtgtcctacaaaggggatcccatcgtacag
caccggccaatgctggaggagaggattgtagagctgtttagaaacttaatgaaaagtgcc
ttcgtggttgagcggcagccctgcatgcctatgcatcctgaccggcccttggtcatcaag
actggcgtccagttcactaccaaagtcagattgctggtcaaattccctgagttaaattat
cagcttaaaattaaagtgtgcattgacaaagactccggggatgttgcagccctcagagga
tcccggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagagtccaac
aacggcagcctgtctgcagaattcaaacacctgaccctgagagagcaaagatgtggtaac
gggggccgagccaattgtgacgcctccctgattgtcaccgaggagctgcacttgatcact
tttgagactgaggtgtatcaccaaggcctcaagatcgaccttgagacccactccttacca
gttgtggtgatctccaacatctgtcagatgccaaatgcctgggcatcgatcctgtggtat
aacatgctgaccaacaaccccaagaacgtgaacttcttcaccaagcccccgattggcacc
tgggatcaagtggccgaggtgcttagctggcagttctcctccaccacgaagcgagggctg
agcatcgagcaattgactacgctggcagagaaactcctaggacctggtgtgaactattca
gggtgtcagattacgtgggctaaattttgcaaagaaaacatggctggcaaaggcttctcc
ttctgggtttggctagacaatatcattgaccttgtgaaaaagtacatcctggctctttgg
aatgaagggtacataatgggttttatcagtaaggagcgagagcgggccatcttgagtacc
aagcccccaggcaccttcctgctacggttcagtgaaagcagcaaagaaggaggtgtcacc
ttcacttgggtggagaaggacatcagtggtaagacccagatccagtcggtggaaccatat
accaagcagcagctgaacaacatgtcgtttgctgaaatcatcatgggctataagatcatg
gatgccaccaacatcctggtgtccccgctggtgtatctctaccccgacattcctaaggag
gaggcgtttggaaagtactgtcgcccagagagccaggagcatcctgaagctgacccaggt
agtgctgccccatacctgaagaccaagtttatctgtgtgacaccaacgacgtgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgagccctcagcaggagggcagttcgagtccctcacgttcgacatggag
ttgacctcggagtgcgctacctccccgatgtga

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