Ailuropoda melanoleuca (giant panda): 100472842 Help Entry 100472842         CDS       T01329                                  Gene name CASP8 Definition (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml01524   Platinum drug resistance aml04115   p53 signaling pathway aml04210   Apoptosis aml04215   Apoptosis - multiple species aml04217   Necroptosis aml04620   Toll-like receptor signaling pathway aml04621   NOD-like receptor signaling pathway aml04622   RIG-I-like receptor signaling pathway aml04625   C-type lectin receptor signaling pathway aml04657   IL-17 signaling pathway aml04668   TNF signaling pathway aml04932   Non-alcoholic fatty liver disease aml05010   Alzheimer disease aml05016   Huntington disease aml05022   Pathways of neurodegeneration - multiple diseases aml05132   Salmonella infection aml05134   Legionellosis aml05142   Chagas disease aml05145   Toxoplasmosis aml05152   Tuberculosis aml05160   Hepatitis C aml05161   Hepatitis B aml05162   Measles aml05163   Human cytomegalovirus infection aml05164   Influenza A aml05165   Human papillomavirus infection aml05167   Kaposi sarcoma-associated herpesvirus infection aml05168   Herpes simplex virus 1 infection aml05169   Epstein-Barr virus infection aml05170   Human immunodeficiency virus 1 infection aml05200   Pathways in cancer aml05203   Viral carcinogenesis aml05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:aml00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     100472842 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100472842 (CASP8)    04215 Apoptosis - multiple species     100472842 (CASP8)    04217 Necroptosis     100472842 (CASP8)    04115 p53 signaling pathway     100472842 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     100472842 (CASP8)    04621 NOD-like receptor signaling pathway     100472842 (CASP8)    04622 RIG-I-like receptor signaling pathway     100472842 (CASP8)    04625 C-type lectin receptor signaling pathway     100472842 (CASP8)    04657 IL-17 signaling pathway     100472842 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100472842 (CASP8)    05203 Viral carcinogenesis     100472842 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     100472842 (CASP8)    05016 Huntington disease     100472842 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     100472842 (CASP8)   09166 Cardiovascular disease    05416 Viral myocarditis     100472842 (CASP8)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     100472842 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     100472842 (CASP8)    05134 Legionellosis     100472842 (CASP8)    05152 Tuberculosis     100472842 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100472842 (CASP8)    05161 Hepatitis B     100472842 (CASP8)    05160 Hepatitis C     100472842 (CASP8)    05164 Influenza A     100472842 (CASP8)    05162 Measles     100472842 (CASP8)    05168 Herpes simplex virus 1 infection     100472842 (CASP8)    05163 Human cytomegalovirus infection     100472842 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     100472842 (CASP8)    05169 Epstein-Barr virus infection     100472842 (CASP8)    05165 Human papillomavirus infection     100472842 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100472842 (CASP8)    05142 Chagas disease     100472842 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100472842 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:aml01002]     100472842 (CASP8) Enzymes [BR:aml01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      100472842 (CASP8) Peptidases and inhibitors [BR:aml01002]  Cysteine peptidases   Family C14: caspase family    100472842 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED Motif Other DBs NCBI-GeneID:  100472842 NCBI-ProteinID:  XP_002915893 Ensembl:  ENSAMEG00000006066 UniProt:  G1LHK8 LinkDB All DBs Position Unknown AA seq 486 aa AA seqDB search MNFSKCLYNIGEQLDSDELASLKFLSMDYIPQKKQEPIKDPLMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLVTYLDTSKEEMEQELQIPGRAQISAYRVMLFQISEDVSKLELRSF KFFLSQEISRCKLHDDLNLFDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREQTLSPQRSLDEISNDMSQLLVGEESLRVLPMSDSPGEQDCEPETSDKVYRMESKPR GYCLIFNNYDFSIARKEVPKLQSIKDRNGTDLDADALCQTFSELHFEIVPFKDCTAKKIC EVLKSYQCMDHSSRDCFICCILSHGDKGIIYGSDGQEVPIYELTSYFTGSKCPSLAGKPK IFFIQACQGDNYQKGIAVETDSEQKEAYLEMDSSYQKRYIPEDADFLLGMATVNNCVSYR NPMEGTWYIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDRKNMGKQMPQPTFTLRKK LFFPLN NT seq 1461 nt NT seq  +upstreamnt  +downstreamnt atgaatttcagcaaatgcctctataatattggagaacagctggacagtgatgagctggcc tccctcaagttcctgagcatggactacatcccacagaagaagcaggaacccatcaaggat cccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggacctgctggttacctacctggac accagcaaggaggagatggagcaggagcttcaaataccaggcagagcccagatctctgcc tacagggtcatgctttttcagatttcagaagatgtaagcaaattggaattgaggtccttt aagttttttttgagccaggagatctccagatgtaaactgcatgatgacttgaacttgttt gatattttcatagagatggagaagagggtcatcctcggggaaagaaatttggataccctg aaaagaatctgtgaccaaattaacaagagcctgctgaagaaaatcacggattatgaagaa ttaagcagagagcaaacactgagccctcaaagaagtctagatgaaatttcaaatgatatg tctcagttgcttgtaggggaggaatccctgagggtactgccaatgtcggactctccagga gaacaggactgtgaaccagagacatcggacaaagtttaccgaatggaaagcaaacctcga ggatattgtttgatctttaacaattacgactttagcatagcacggaaggaagtgcccaaa cttcagagcattaaggataggaatgggacagacttggatgcagatgctttgtgtcagacc tttagtgagcttcattttgagatcgtgcctttcaaagactgtacagccaagaaaatctgt gaggttctgaaatcctaccaatgcatggaccactctagcagggattgctttatctgctgc atcctctcccatggagacaagggcatcatctatggctctgatgggcaagaagtccccatc tatgagctgacttcttacttcactggttcaaagtgcccttcccttgcaggcaagcccaaa atcttttttattcaggcttgtcaaggggataactaccagaaaggtatagctgttgagact gactctgaacagaaggaagcctatttagaaatggactcatcctatcagaagagatatatc ccagaagacgctgactttctgctggggatggccactgtgaataattgtgtttcctaccga aaccccatggaaggaacctggtatatccagtcactttgccagagcctgagagaaagatgt cctaggggcgaagatattctcaccatccttaccgaggtgaactttgaagtgagcaataag gatgacaggaaaaacatggggaaacaaatgccacaacctactttcacactgaggaaaaaa ctctttttccctcttaattga

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