KEGG   Ailuropoda melanoleuca (giant panda): 100475698
Entry
100475698         CDS       T01329                                 

Gene name
TGFBR1
Definition
(RefSeq) TGF-beta receptor type-1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml04010  MAPK signaling pathway
aml04060  Cytokine-cytokine receptor interaction
aml04068  FoxO signaling pathway
aml04144  Endocytosis
aml04218  Cellular senescence
aml04350  TGF-beta signaling pathway
aml04371  Apelin signaling pathway
aml04380  Osteoclast differentiation
aml04390  Hippo signaling pathway
aml04520  Adherens junction
aml04659  Th17 cell differentiation
aml04926  Relaxin signaling pathway
aml04933  AGE-RAGE signaling pathway in diabetic complications
aml05142  Chagas disease
aml05161  Hepatitis B
aml05166  Human T-cell leukemia virus 1 infection
aml05200  Pathways in cancer
aml05210  Colorectal cancer
aml05212  Pancreatic cancer
aml05220  Chronic myeloid leukemia
aml05225  Hepatocellular carcinoma
aml05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100475698 (TGFBR1)
   04350 TGF-beta signaling pathway
    100475698 (TGFBR1)
   04390 Hippo signaling pathway
    100475698 (TGFBR1)
   04371 Apelin signaling pathway
    100475698 (TGFBR1)
   04068 FoxO signaling pathway
    100475698 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100475698 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100475698 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    100475698 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    100475698 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100475698 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    100475698 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100475698 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100475698 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100475698 (TGFBR1)
   05212 Pancreatic cancer
    100475698 (TGFBR1)
   05225 Hepatocellular carcinoma
    100475698 (TGFBR1)
   05226 Gastric cancer
    100475698 (TGFBR1)
   05220 Chronic myeloid leukemia
    100475698 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100475698 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100475698 (TGFBR1)
   05161 Hepatitis B
    100475698 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    100475698 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aml01001]
    100475698 (TGFBR1)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     100475698 (TGFBR1)
Protein kinases [BR:aml01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   100475698 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2
Other DBs
NCBI-GeneID: 100475698
NCBI-ProteinID: XP_034521455
Ensembl: ENSAMEG00000004381
LinkDB
Position
7
AA seq 489 aa
HIVNLENFFLIESCSLFPALQCFCHLCTKDNFTCVTDGLCFVSVTETTDKVIHNSMCIAE
IDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTVGKPSSGLGPVELAAVIAGPV
CFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLP
LLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVML
RHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLA
HLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVG
TKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPS
DPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ
LSQQEGIKM
NT seq 1470 nt   +upstreamnt  +downstreamnt
cacattgttaacctggagaacttttttctaatagaatcttgttctctttttccagcatta
cagtgtttctgccacctttgtacaaaagataattttacgtgtgtgacagatgggctctgc
tttgtctctgtcacagagaccacagacaaagttatacacaatagcatgtgtatagctgaa
attgacctaattcctcgagacagaccatttgtatgtgcaccgtcttcaaaaactgggtct
gttactacaacctattgctgcaaccaggaccattgcaataaaatagaactcccaactgtt
ggaaagccatcatctggccttggccccgtcgaattggcagctgtcattgctggaccagtc
tgctttgtctgcatctcgctcatgttgatggtttatatctgccataaccgtactgtcatt
caccatcgagtgccaaatgaagaggatccttccttagatcgtccttttatttcagagggc
actacattaaaagatttaatttatgatatgacgacatcaggttctggatcaggtttacca
ttgcttgttcagagaacaattgcaagaactattgtgttacaagaaagtattggcaaaggt
cgatttggagaagtttggcgaggaaagtggagaggagaagaagttgctgttaaaatattc
tcctctagagaagagcgctcatggttccgtgaggcagagatttatcagaccgtaatgtta
cgtcatgaaaacatcttgggatttatagcagcagacaataaagacaatggtacatggact
cagctctggttggtgtcagattatcatgagcatggatccctttttgattatttgaacaga
tacacagttactgtggaaggaatgataaaactcgctttgtccacagcaagtggacttgcc
catctccacatggagatcgttggtacccaagggaaaccagccattgctcatagagatttg
aaatccaagaatatcttggtaaagaagaatggaacttgctgtattgcagacttaggactg
gcagtgagacacgattcggccacagatacgattgatattgctccaaatcacagagtggga
acaaaaaggtacatggcccctgaagttctagatgattccataaatatgaaacactttgaa
tccttcaaacgtgccgacatctatgcaatgggcttagtattctgggaaatagctcgacga
tgttccattggtggaattcatgaagattaccagctgccttattatgatcttgtaccttct
gatccgtcagttgaagaaatgagaaaagttgtttgtgaacagaagttaaggccaaatatt
ccaaacagatggcagagttgtgaagccctgagggtaatggctaaaattatgagagaatgt
tggtatgccaacggagcagcgaggcttacggctttgcggattaagaaaacattgtcacaa
ctcagtcaacaggaaggcatcaaaatgtag

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