Amycolatopsis mediterranei S699: AMES_2245
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Entry
AMES_2245 CDS
T02190
Symbol
hisA
Name
(GenBank) phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
KO
K24017
phosphoribosyl isomerase A [EC:
5.3.1.16
5.3.1.24
]
Organism
amm
Amycolatopsis mediterranei S699
Pathway
amm00340
Histidine metabolism
amm00400
Phenylalanine, tyrosine and tryptophan biosynthesis
amm01100
Metabolic pathways
amm01110
Biosynthesis of secondary metabolites
amm01230
Biosynthesis of amino acids
Module
amm_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
amm00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
AMES_2245 (hisA)
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
AMES_2245 (hisA)
Enzymes [BR:
amm01000
]
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.1 Interconverting aldoses and ketoses, and related compounds
5.3.1.16 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
AMES_2245 (hisA)
5.3.1.24 phosphoribosylanthranilate isomerase
AMES_2245 (hisA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
His_biosynth
NMO
DHO_dh
DUF6108
Motif
Other DBs
NCBI-ProteinID:
AFO75781
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Position
2432319..2433026
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AA seq
235 aa
AA seq
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MADGQAVRLVQGEAGTETSYGSPLEAALAWQRDGAEWIHLVDLDAAFGKGSNRELLAEVV
GRLDVQVELSGGIRDDASLKAALDTGARRVNLGTAALEDPEWTSRVIGEYGDRVAIGLDV
RITEAGHRLSARGWTSDGGDLWDVLERLDRDGASRYVVTDVSKDGTLRGPNLELLRDVVA
RTDAPVIASGGVSSVADLVALAGLAADGVEGSIVGKALYAGAFTLPEALAAVAKL
NT seq
708 nt
NT seq
+upstream
nt +downstream
nt
gtggccgatggccaggccgtgcgactcgtccagggcgaggccggcaccgagacctcctat
ggcagcccgctggaggccgcgctggcctggcagcgcgacggcgccgagtggatccacctg
gtcgacctcgacgccgcgttcggcaagggcagcaaccgcgagctgctcgccgaggtcgtc
ggccggctcgacgtgcaggtcgagctctccggcggcatccgcgacgacgcgtcgctgaag
gccgcactggacaccggggcccggcgggtcaacctcggcaccgccgcgctcgaagacccg
gagtggaccagccgggtcatcggcgagtacggcgaccgcgtcgcgatcggcctcgacgtg
cggatcaccgaggccggccaccggctttcggcccgcggctggacctccgacggcggcgac
ctgtgggacgtcctggagcgcctcgaccgcgacggcgcgtcccgctacgtcgtcaccgac
gtcagcaaggacggcacgctgcgcggcccgaacctcgagctgctgcgcgacgtcgtcgcc
cgcacggacgcaccggtgatcgcctccggtggggtgtcgagcgtggccgacctcgtcgcc
ctggcgggcttggcggccgacggcgtcgaggggtccatcgtcggcaaggcgctctacgcc
ggcgcgttcacgctgccggaggccctcgccgcggtcgcgaagctctag
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