Amycolatopsis methanolica: AMETH_0138
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Entry
AMETH_0138 CDS
T03230
Symbol
pdhB
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring)
KO
K00167
2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:
1.2.4.4
]
Organism
amq
Amycolatopsis methanolica
Pathway
amq00280
Valine, leucine and isoleucine degradation
amq00640
Propanoate metabolism
amq00785
Lipoic acid metabolism
amq01100
Metabolic pathways
amq01110
Biosynthesis of secondary metabolites
amq01210
2-Oxocarboxylic acid metabolism
Module
amq_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
AMETH_0138 (pdhB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
AMETH_0138 (pdhB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AMETH_0138 (pdhB)
Enzymes [BR:
amq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
AMETH_0138 (pdhB)
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Motif
Pfam:
Transket_pyr
Transketolase_C
PFOR_II
Motif
Other DBs
NCBI-ProteinID:
AIJ20230
UniProt:
A0A076MMZ5
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Position
complement(129696..130724)
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AA seq
342 aa
AA seq
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MAAPVKSPVDGAVPAMQKLTIGKALNLGLRAAMEADDKVIVLGEDVGKLGGVFRITDGLQ
KDFGEQRVLDTPLAESGIIGTAVGLAVRGFRPVCEIQFEGFIFPGFDQISSQLAKLHYRT
QGKVKVPVVVRVPFGGGIGAVEHHSESPESLFAHIPGLKVVSCSNPADAYWMIQQAIDCD
DPVLFFEPKRLYHNGQLKSEVDTTTPPGPLFASRVVRQGTDCTVVAYGPSVKVCLDAAEA
AAEEGRSLEVIDLRTISPLDLAPVFESVRRTGRLVAVSEASSESSITSEIAARVQQECFY
SLEAPVLRATGFDTPYPPSKLEEHFLPDLDRVLHTVDRAMGW
NT seq
1029 nt
NT seq
+upstream
nt +downstream
nt
atggccgcccccgtcaagtcccctgtggacggtgcagtgcccgcgatgcagaagctgacc
atcggcaaggctctgaacctgggcctgcgtgccgcgatggaggccgacgacaaggtcatc
gtcctcggtgaggacgtcggcaagctcggcggcgtcttccgcatcaccgacgggctgcag
aaggacttcggcgagcagcgcgtgctggacacgccgctggccgagtccggcatcatcggc
accgcggtcggtctcgccgtgcgcgggttccggccggtgtgcgagatccagttcgagggc
ttcatcttccccggcttcgaccagatctcctcgcagctggcgaagctgcactaccggacc
cagggcaaggtcaaggtcccggtggtcgtgcgggtgcccttcggcggcgggatcggcgcg
gtcgagcaccactccgagtcgccggagtcgctgttcgcgcacatccccgggctgaaggtc
gtgtcgtgctccaacccggccgacgcgtactggatgatccagcaggccatcgactgcgac
gacccggtgctgttcttcgagccgaagcggctctaccacaacgggcagctcaagtccgaa
gtggacaccacgacgccgccggggccgctgttcgcctcccgggtggtgcgccagggcacc
gactgcacggtggtcgcctacgggccgtcggtgaaggtgtgcctggatgcggccgaggcc
gcggcagaagagggccggtcgctggaggtcatcgacctgcgcacgatctcgccgctcgac
ctcgcgccggtgttcgagtcggtgcgccgtaccgggcggctggtcgcggtcagcgaggcg
tcgtcggagtcgtcgatcacctcggagatcgccgcgcgcgtgcagcaggagtgcttctac
tcgctggaagcgccggtgctgcgggccaccgggttcgacaccccgtacccgccgtccaag
ctcgaggagcacttcctccccgacctggaccgggtgctgcacaccgtcgaccgcgcgatg
ggctggtga
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