KEGG   Alligator sinensis (Chinese alligator): 102368409Help
Entry
102368409         CDS       T02922                                 

Gene name
DOT1L
Definition
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
  KO
K11427  histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:2.1.1.43]
Organism
asn  Alligator sinensis (Chinese alligator)
Pathway
asn00310  Lysine degradation
Brite
KEGG Orthology (KO) [BR:asn00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    102368409 (DOT1L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:asn03036]
    102368409 (DOT1L)
Enzymes [BR:asn01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     102368409 (DOT1L)
Chromosome and associated proteins [BR:asn03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     102368409 (DOT1L)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DOT1
Motif
Other DBs
NCBI-GeneID: 102368409
NCBI-ProteinID: XP_014382022
UniProt: A0A1U8DLD0
LinkDB All DBs
Position
Unknown
AA seq 1745 aa AA seqDB search
MTCKTSQVVFPCLREVTSRHHAHKTFMVHTPDKHHDAAHEIIETIRWVCEEIPDLKLAME
NYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYN
HSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAA
TNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTS
VIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVEL
SPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTP
TKVHENKDSGPEEEKAGANTIKKPSPSKARKKKLSKKGRKMAGRKRGRPKKMNAANTDRK
TKKNQTALELLHAQTVSQTSSSSPQDAYKSPHSPYYQLPPKVQRHSSNQLLVTPTPPALQ
KLLDSFKIQYMQFMAYMKTPQYKANLQQLLEQEKEKNVQLLGTAQQLFTHCQAQKEEIKR
LFQQKLDELGVKALTYNDLIQAQKEISAHNQQLKEQTKQLEKDNSELRNQSLQLLKARCE
ELKLDWSTLSLENLLKEKQALKNQISEKQKHCLELQISIVELEKSQRQQELMQLKSCTPS
DESLSIQLRNKNHLSREPEVDHGRFQLELECSKFPMTHINGMSPELSMNGHATPYEIHNT
LSRPSSKQNTPQYMTSHLDQEIVPCTPNHSSRQKADKTSSLSLPDYTRFSPAKIALRRHL
NQDHAVNGKATTNEIQRADHIKENGLTYPSPNISNGMKLSPQETRPSSPAALPIAGEKVL
RERTSASNGETITSLPISIPLSTVQPNKLPVSIPLASVVLPSRVEKVVTHQGPVHQNRDS
STLEKQIGASSHNGISNAAGNKPLALATSGFSYSSGSVAVNGTLSNSPAQLNHSVDQAAL
DDSGSLFNSVGSRSSTPQHPLLMMQSRNSGQNSPAHQHSTSPRLNGASQSLVGVLQYADA
QKMFAEGTKGDLQSDAAFSDPENEAKRRIIFTISPNTGNVKQSPSNKHSPLTSSIRLDCG
QAYVQDGKKRGRRKRSSTGNLSVSSGVSPKRKSLPTVAGLFTQPSGSPLNINSMVNNINQ
PLEITAISSPENSLKNSPVPYQDNDQPPVLKKEKPLIQTNGIHYSPLTSDEEQGSEDEHN
STRIERKIATISLESKSPQKTVENGGSLAGRKQAQTSENMNSSKWKSTFSPISDINLTKT
TDSPLQAVSSLSQNSLFAFRPSSEDGMAIDSKITAHARKNVTMPSSGTDGLSPNTNAANG
FTYNGGLTTDIGLHSFIDGASLPHKTSDVTSLNSSLSFQSQRSKDLGVSETNPFLNKRQL
EGLGSMKGEDLNRSGVKSKEMSELNIRTGGSSEKSSLQHNGKASKGRDRDVEFKNGHNLF
ISAAAVSSGGLLNGKSLSTAVSSAGNPASVQTHHPFLNTLTTGSQFPLGPMALPANLNSV
TNSSVLQSLFNTMPAAASLVHVSSAATRLTNSHTMGNFSSGVTGGTVGGIFNHAVPSASS
SHQFGASFSSSAVSSSTMLSLNPLQAVATTSSSSFQSPSSSLVTSSENRPAQHLNRAPVQ
SVFHTPPPPPPNISLPPPPPLLTSNSEPALLQNLPSIPANEAFLPSSSAASVQSANASLS
IKLASLQHKTSRPSFTVHHPPLPRLALAQTAPMIPQSNATGTSAMWVTLGMQSPYASHLS
GVKPR
NT seq 5238 nt NT seq  +upstreamnt  +downstreamnt
atgacctgcaaaacctctcaagtggtttttccttgcttgagagaagtgacatctcgacat
catgcccataagacttttatggtgcacactcctgacaaacaccatgatgctgctcatgaa
atcattgagacaattcggtgggtctgtgaagaaatcccagatctcaagcttgctatggaa
aattatgttttaattgactatgatacaaaaagctttgaaagcatgcagaggctttgtgac
aaatacaaccgagccattgatagcattcatcagttgtggaaaggaaccacccagcccatg
aaactgaacactcgtccttccaatggactcctccgtcatatcctgcagcaagtatataac
cactcggtgaccgacccagagaaactcaacaactatgaacccttttccccagaggtgtat
ggagaaacttcctttgatttagtggcccaaatgattgatgaaattaagatgacagaggat
gacttgtttgttgatttgggcagtggtgtgggtcaggtggtgctccaagttgctgcagcc
acaaactgcaaacatcactatggtgtggagaaagctgatattccagccaaatatgctgag
acgatggacagagagttcagaaagtggatgaaatggtatgggaaaaaacatgcagaatac
acactggaaagaggtgacttcctctcagaagaatggagagagcgaattgcaaacacaagt
gttatttttgtgaataattttgcctttggtcctgaggtggatcaccaactgaaggagcga
tttgcaaacatgaaggaaggtggcagaatcgtgtcctcaaaaccttttgcacctctgaat
tttagaataaatagtcgaaacttgagtgatattggcactataatgagagttgtggaatta
tcaccactgaaagggtctgtttcatggacagggaaaccagtttcctactacctgcatact
attgatcgaaccatacttgaaaactatttttctagtctcaaaaatccaaaactcagggag
gaacaagaggcagctagacgtcgtcagcaaagagaaaacaagagcaacacaacaactccg
acaaaggtgcacgaaaacaaggattctggtcctgaagaagaaaaagctggggcaaacacc
attaagaagccatctccctccaaagcacgcaagaagaagctgagtaaaaaaggaaggaaa
atggcaggcaggaaacgagggcgtcctaagaagatgaacgctgcaaatacggaccgcaag
accaagaagaaccaaactgcactggagcttctgcatgctcaaactgtgtcacagacatcc
tcatcctctcctcaggatgcatacaagtcacctcatagtccatattaccaactacctccg
aaggtgcaacggcattcatctaaccagctgttggtgactcccaccccacctgcactacag
aagctgctagactcttttaagatccagtacatgcagttcatggcgtacatgaaaactcct
cagtacaaagctaacctgcaacagttattggagcaggaaaaggaaaagaacgttcagtta
ttggggacagcgcagcagttgttcacccattgccaggcccaaaaagaggaaatcaagcga
ctgtttcaacaaaagctcgatgagttgggagttaaggctctgacatataatgacctgatt
caggctcagaaggagatctctgctcacaaccagcagctgaaagaacagacgaagcagctg
gagaaagataacagtgaactcaggaaccagagcttgcagctgcttaaggcacggtgtgaa
gaactgaaattggactggtcaactctttcacttgagaacttactgaaggaaaaacaggcg
ctgaagaatcagatttcggagaaacaaaagcactgcttggaattgcagatcagcattgtg
gagcttgagaaaagtcaaaggcagcaggagctcatgcagctgaaatcctgtacgccgtcc
gatgagtccttgtcgatacaactacgcaataaaaatcatctaagtcgtgaacctgaggtt
gatcatggcaggttccaacttgagcttgagtgttctaaatttcctatgacccatatcaat
ggcatgagtcccgaactgtccatgaatggccatgctactccctatgaaatccataatact
cttagccggccctcttccaagcaaaacacccctcagtatatgacttctcacctggaccaa
gaaatagttccatgtaccccaaaccatagcagtagacagaaggcggacaagacatccagc
ttgtccttacctgattataccagattttcccctgctaagatagccctaaggaggcacttg
aatcaggaccatgcagtcaatggaaaagcaacaactaatgaaattcagagagctgaccac
ataaaagagaatggccttacatatccaagccctaatatttcaaatggcatgaagctgagt
cctcaggaaactcggccctcttccccagcggccttaccgattgcaggcgagaaggtttta
agagagagaacctctgcaagtaatggagaaactatcaccagcctacctatcagtattcct
ctcagcacagtgcagcccaataaactccctgttagtatccctctggccagcgtagtccta
cctagccgtgttgagaaggtggtgacacaccaaggtccagttcatcagaatagagactca
tcaacacttgaaaagcagattggtgctagttctcataatggcataagcaatgctgctgga
aacaagccactggctttggctacctcaggtttttcttattcttctggctccgtggcagtc
aatggaactctttcaaacagcccagcccaacttaaccatagtgttgatcaggcagctctg
gacgactctgggagtctgtttaactcggtagggtctcggagttccactccacaacaccct
ttgctaatgatgcagtcacggaactcggggcaaaactcccctgctcaccagcactcaaca
agccccaggttaaacggagcctcccagagcctggtaggggtattgcagtatgcagatgct
cagaagatgtttgctgaaggaacaaagggggatcttcagtctgatgcagcattttcagat
cccgagaacgaggccaagagaagaatcatctttacaatctctcctaatacaggaaatgta
aaacaatctccttccaacaagcacagtcccctgacctcgagcattcggctggactgtggt
caagcatacgtgcaagatgggaagaaacgaggtcgaaggaagagatcttctactgggaat
ctcagcgtgagctctggggtgtcccccaaacgcaaatccttaccaacagtggctggactg
tttactcagccttcagggtcaccactcaatattaactccatggtcaataacattaatcag
cctttagaaataacagccatttcctcccctgaaaactccctgaagaactctcctgttccc
taccaggacaatgaccagcccccagtgctgaaaaaggagaagcccctcattcagaccaat
ggcattcattactcgccgctgacatctgatgaagagcaggggtctgaagatgagcacaat
agtaccagaattgagagaaaaattgcaacaatatcattggaaagcaaatctccacaaaag
actgttgaaaatggtggcagtttagctggaagaaaacaagcgcaaaccagcgagaacatg
aatagcagtaaatggaagtctaccttttcaccaatatctgacatcaacctgaccaaaact
acagatagtcccttgcaggctgtttcatctctgagccagaattcactgtttgccttcagg
ccatcctctgaggatggcatggccattgacagcaagatcacggcacatgcgagaaaaaat
gtcaccatgccctcctctggaacagatggactcagccccaacacaaatgctgcaaatgga
ttcacgtacaacggtggactgacgacagatattggtttacacagctttattgatggtgct
tctcttcctcataagacttcagatgtgacttcccttaattcctctctgagttttcagtct
cagcggagcaaagacttgggtgtctcagagacaaatccctttttgaacaagaggcagctt
gaaggcctaggcagcatgaaaggggaagacttaaatcggtcaggggtcaaaagcaaagag
atgagcgaattaaacattcgtacagggggctcttcagaaaaaagctctttgcagcataat
ggaaaggccagcaaaggacgggaccgagatgtggagtttaaaaatggccacaaccttttc
atttctgctgctgctgtatcttcgggtggccttctaaatggcaaaagcctttccactgct
gtttcctcagcaggcaacccagcatctgttcagacacaccatcctttcttaaacactttg
accactggatcacagttcccccttggccccatggccttgccagcaaacctcaactcggtg
acgaactcttcagtattgcagtctttatttaatacaatgccagctgctgccagtctggtc
cacgtgtcatcagctgcaaccagactgactaattctcacactatggggaacttctcttct
ggggttacaggtggaacagttggaggtatttttaaccatgcggtgccttctgcctcctct
tctcatcaatttggagccagtttcagcagcagtgctgtctctagcagcacaatgctaagc
ttaaaccctctgcaggctgttgccaccacctcatcctcatccttccagtccccctcctct
agcttagtaacatctagtgagaacagacctgcccagcacctaaacagagctccagtgcaa
tctgtttttcatacccctcctcccccacctcctaacatttcattgccacctcctcctcca
ttactcacttctaactctgagcctgcgcttctgcagaacttgccgtccattccagctaac
gaagcttttttaccatcatcttctgctgcttctgtccaatctgctaatgcttctttgtct
attaagctagcttctcttcagcacaaaacttcccgtccctcctttacagtccatcaccct
cctctgccccgtttggcgctggcacagaccgcgcccatgatcccgcagtccaacgcaacc
ggcacgtctgctatgtgggttacacttggcatgcagtctccttatgcttcgcacctttct
ggggttaagccacgataa

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