KEGG   Anaerolinea thermophila: ANT_03310
Entry
ANT_03310         CDS       T01410                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
atm  Anaerolinea thermophila
Pathway
atm00290  Valine, leucine and isoleucine biosynthesis
atm00660  C5-Branched dibasic acid metabolism
atm01100  Metabolic pathways
atm01110  Biosynthesis of secondary metabolites
atm01210  2-Oxocarboxylic acid metabolism
atm01230  Biosynthesis of amino acids
Module
atm_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:atm00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    ANT_03310 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    ANT_03310 (leuC)
Enzymes [BR:atm01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     ANT_03310 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     ANT_03310 (leuC)
SSDB
Motif
Pfam: Aconitase AcnX
Other DBs
NCBI-ProteinID: BAJ62365
UniProt: E8N030
LinkDB
Position
357083..358510
AA seq 475 aa
MNAPKTLFEKIWERHVVVEPPDSPAVLYIDLHLVHEVTSPQAFSGLRARGLRVRRPERTV
ATMDHGVPTLSQGGNGSGRLAFADELSRRQIQQLQDNCREFGIRLMDLESPNQGIVHVIG
PDLGLTQPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQCLLQRRPKTCAVRIEG
RLNKGVTAKDVILALIAQIGTAGGTGYVFEYMGEAVRAMSMEERMTLCNMSIEGGARAGM
VAPDDTTFEYLAGRPFAPQGEAWERAVAYWRTLPSDEGAVFDRTVTLDASQLEPMVTYGT
NPGMGVPISGCIPTPDEMKDASQRAALEKALGYMDLRPGAPIQGQRVDVVFIGSCTNGRL
ADLRSAARLFKGRRVAPGVRVLVVPGSQQVKRAAEAEGLDRVFKEAGAEWREPGCSMCIA
MNGDQLEPGQYAISTSNRNFEGRQGKGGRTFLASPLTAAASALTGVITDPRPLLS
NT seq 1428 nt   +upstreamnt  +downstreamnt
atgaacgcccccaagacgttgtttgagaaaatctgggaacgtcatgtggttgtcgagccg
cccgactctccggcggtgctgtacattgacctgcatctggtgcatgaagtgacttcgccg
caggccttcagtggattgcgggcgcgcgggttgcgggtgcgccgaccggagcgcaccgtc
gccaccatggatcacggtgtgcctacgctttcgcagggtgggaatggcagtgggcggctc
gcctttgccgatgaactgagccgccgccagattcagcagttgcaggacaactgccgcgag
tttggcatccgtctgatggatctggaaagccccaaccagggcatcgtgcatgtcatcggt
cccgatttgggcttgacccagccgggcatgaccatcgtctgcggcgacagccacaccgcc
acacacggcgcgtttggcgcgctggcgttcggcatcggcaccagcgaggtggagcatgtg
cttgccacgcagtgcctgcttcagcgccgaccgaaaacctgtgccgtgcgcatcgagggg
cgcctgaacaagggcgtgaccgccaaggatgtcatcctggcgctgattgcccaaatcggc
acggcgggcggcacgggctacgtctttgagtacatgggcgaagccgtacgcgccatgagc
atggaagagcgcatgaccctgtgcaacatgtccatcgagggcggtgcccgcgcgggcatg
gtggctccggacgataccacctttgaatatctggcaggacgtccctttgcgccgcaggga
gaagcctgggagcgcgctgtggcgtactggcgcaccctgccgagcgatgaaggggcggtc
tttgaccgcacggtgacgctggatgcatctcaactcgagccgatggtcacctacggcacc
aatccgggcatgggggtgcccatcagcggatgcatccccacgccggacgagatgaaggac
gccagccagcgcgccgcgctggaaaaagctctggggtacatggatttgcgtcccggcgcc
ccaatccagggtcagcgtgtggatgtggtctttatcggttcgtgcaccaacggacgtctt
gccgatttgcgcagtgccgcgcgcttgttcaaaggcaggcgggttgcccccggggtgcgc
gtgctggtggtgccgggttcgcaacaggtcaaacgcgccgccgaagccgaaggactggat
cgggtgttcaaagaagccggcgccgagtggcgcgaaccggggtgctcgatgtgcatcgcc
atgaacggcgaccaactggagccagggcagtatgctatcagcaccagcaatcgcaatttt
gaggggcgtcagggcaagggcgggcgcaccttccttgccagcccgctgaccgccgctgct
tcggcgctcaccggggtcatcaccgacccgcgccctctgctttcctga

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