KEGG   Balaenoptera acutorostrata scammoni (minke whale): 102998704Help
Entry
102998704         CDS       T03086                                 

Gene name
PTEN
Definition
(RefSeq) phosphatase and tensin homolog
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
bacu  Balaenoptera acutorostrata scammoni (minke whale)
Pathway
bacu00562  Inositol phosphate metabolism
bacu01100  Metabolic pathways
bacu01521  EGFR tyrosine kinase inhibitor resistance
bacu04068  FoxO signaling pathway
bacu04070  Phosphatidylinositol signaling system
bacu04071  Sphingolipid signaling pathway
bacu04115  p53 signaling pathway
bacu04140  Autophagy - animal
bacu04150  mTOR signaling pathway
bacu04151  PI3K-Akt signaling pathway
bacu04218  Cellular senescence
bacu04510  Focal adhesion
bacu04931  Insulin resistance
bacu05165  Human papillomavirus infection
bacu05166  Human T-cell leukemia virus 1 infection
bacu05200  Pathways in cancer
bacu05206  MicroRNAs in cancer
bacu05213  Endometrial cancer
bacu05214  Glioma
bacu05215  Prostate cancer
bacu05218  Melanoma
bacu05222  Small cell lung cancer
bacu05224  Breast cancer
bacu05225  Hepatocellular carcinoma
bacu05230  Central carbon metabolism in cancer
bacu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:bacu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102998704 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    102998704 (PTEN)
   04070 Phosphatidylinositol signaling system
    102998704 (PTEN)
   04071 Sphingolipid signaling pathway
    102998704 (PTEN)
   04151 PI3K-Akt signaling pathway
    102998704 (PTEN)
   04150 mTOR signaling pathway
    102998704 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102998704 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    102998704 (PTEN)
   04218 Cellular senescence
    102998704 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102998704 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102998704 (PTEN)
   05206 MicroRNAs in cancer
    102998704 (PTEN)
   05230 Central carbon metabolism in cancer
    102998704 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102998704 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    102998704 (PTEN)
   05214 Glioma
    102998704 (PTEN)
   05218 Melanoma
    102998704 (PTEN)
   05215 Prostate cancer
    102998704 (PTEN)
   05213 Endometrial cancer
    102998704 (PTEN)
   05224 Breast cancer
    102998704 (PTEN)
   05222 Small cell lung cancer
    102998704 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    102998704 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102998704 (PTEN)
   05165 Human papillomavirus infection
    102998704 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102998704 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:bacu01009]
    102998704 (PTEN)
Enzymes [BR:bacu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     102998704 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     102998704 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     102998704 (PTEN)
Protein phosphatases and associated proteins [BR:bacu01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    102998704 (PTEN)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PTEN_C2 DSPc Y_phosphatase Y_phosphatase3 PTPlike_phytase DUF3256
Motif
Other DBs
NCBI-GeneID: 102998704
NCBI-ProteinID: XP_007179216
UniProt: A0A383ZVY4
LinkDB All DBs
Position
Un
AA seq 403 aa AA seqDB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq 1212 nt NT seq  +upstreamnt  +downstreamnt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatggggtttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctatgtgctgaaagacattatgataccgccaaa
tttaactgcagagttgcacagtatcctttcgaagaccataatccaccacagctagaactt
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgtagca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgcgcgtatttgtta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtatattattatagctac
ctgttaaagaatcatctggattatagaccagtggcattgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggacccacacgacgggaagacaagttcatgtac
tttgagttccctcagccgttgcctgtgtgtggtgacatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaatacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagtatttgcagtatagagcgtgcagataatgacaaggaatatctagtactcacttta
acaaaaaatgatctcgacaaagcaaataaagacaaggccaaccgatacttttctccaaat
tttaaggtgaagctgtacttcacaaaaacagtagaggagccatcaaatccagaggctagc
agttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcatacacaaatt
acaaaagtctga

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