KEGG T03086: 102998750

KEGG Orthology (KO) [BR:bacu00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102998750 (RPS6KB2)
   04350 TGF-beta signaling pathway
    102998750 (RPS6KB2)
   04371 Apelin signaling pathway
    102998750 (RPS6KB2)
   04066 HIF-1 signaling pathway
    102998750 (RPS6KB2)
   04151 PI3K-Akt signaling pathway
    102998750 (RPS6KB2)
   04152 AMPK signaling pathway
    102998750 (RPS6KB2)
   04150 mTOR signaling pathway
    102998750 (RPS6KB2)
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102998750 (RPS6KB2)
09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    102998750 (RPS6KB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102998750 (RPS6KB2)
  09149 Aging
   04211 Longevity regulating pathway
    102998750 (RPS6KB2)
   04213 Longevity regulating pathway - multiple species
    102998750 (RPS6KB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    102998750 (RPS6KB2)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102998750 (RPS6KB2)
   05205 Proteoglycans in cancer
    102998750 (RPS6KB2)
   05231 Choline metabolism in cancer
    102998750 (RPS6KB2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102998750 (RPS6KB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102998750 (RPS6KB2)
   05212 Pancreatic cancer
    102998750 (RPS6KB2)
   05225 Hepatocellular carcinoma
    102998750 (RPS6KB2)
   05226 Gastric cancer
    102998750 (RPS6KB2)
   05221 Acute myeloid leukemia
    102998750 (RPS6KB2)
   05224 Breast cancer
    102998750 (RPS6KB2)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    102998750 (RPS6KB2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102998750 (RPS6KB2)
   05163 Human cytomegalovirus infection
    102998750 (RPS6KB2)
   05165 Human papillomavirus infection
    102998750 (RPS6KB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102998750 (RPS6KB2)
   01522 Endocrine resistance
    102998750 (RPS6KB2)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bacu01001]
    102998750 (RPS6KB2)
Enzymes [BR:bacu01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102998750 (RPS6KB2)
Protein kinases [BR:bacu01001]
Serine/threonine kinases: AGC group
  RSK family [OT]
   102998750 (RPS6KB2)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal Seadorna_VP7 Kdo

Other DBs

NCBI-GeneID:

102998750

NCBI-ProteinID:

XP_007171124

UniProt:

A0A383Z8C1

LinkDB

Position

AA seq 590 aa
MHLDSAPSKVKVALEPKWSACRRPLSCAAPGEAVLGRLRGPRKKVRRALAPLHSGTTIPE
MPCDGRQLFSPPARGRGSLLRHRCARPPSRSDDVRPGPACQSERGWVSAWGPAGPAQPWR
RCLTWTWRRRKAARARASQSSAPRPVGRYEEVELTESSVNPGPERIGPHCFELLRVLGKG
NYGKVFQVRKVQGTNVGRIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAY
AFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLSEITLALGHLHSQGIIYRDLK
PENIMLNSQGHIKLTDFGLCKESIHEGAVTPTFCGTIEYMAPEILVRSGHNRAVDWWSLG
ALMYDMLTGSPPFTAENRKKTMDKIIRGKLELPAYLTPDARDLVKKFLKRNPSQRIGGGP
GDAADVQRHPFFRHVNWDDLLARRVDPPFRPSLQSEEDVSQFDSHFTRQTPVDSPDDTAL
SESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPWTPISPLKFSPFEGFRPS
PGPPEPPEPPLPPLLLPLLPPPPPSSTAPLPIRPPSGTKKSKKGRGRPGR

NT seq 1773 nt +upstreamnt +downstreamnt
atgcacttggactctgccccgtccaaagtcaaagtcgccctagaaccaaaatggtcggct
tgcaggaggcccttgtcctgtgccgccccgggggaagctgtgctgggaagactgaggggc
ccgcggaagaaggttcggcgggctttagcacccctgcactcaggaactaccattcccgag
atgccttgtgacggacgccaacttttctcgcctccggctcgcgggaggggcagcctcttg
cgtcatcggtgcgcgaggccgccgtcgcggagtgatgacgtaaggcccgggccggcctgt
cagtcagagcgcggctgggtaagcgcctgggggcccgcggggccggcgcagccatggcgg
cggtgtttgacctggacctggagacggaggaaggcagcgagggcgagggcgagccagagt
tcagccccgcggcctgtgggacgctatgaggaggtggagctgactgagagcagtgtgaac
ccgggccctgagcgcatcgggccccactgctttgagctgctgcgtgtgctgggcaagggg
aactatggcaaggtgttccaggtgcgaaaggtgcagggcaccaatgtgggcagaatatat
gccatgaaagtcctgaggaaggccaaaattgtgcgcaacgccaaggacacggcgcacacg
cgggctgagcggaacattctagagtcagtgaagcaccccttcattgtggaactggcctat
gccttccagactggcggcaaactctacctcatcctggagtgcctcagtggcggcgagctc
ttcacacatctggagcgagagggcatcttcctggaagacacggcctgtttctacctgtca
gagatcacactggccctgggccatctccactcccaaggcatcatctaccgggatctcaaa
cctgagaacatcatgctcaacagccagggtcacatcaaactgacggacttcggcctctgc
aaggagtcgattcacgagggtgccgtcacccccaccttctgcggcaccattgagtacatg
gcccctgagattctggtgcgcagtggccacaatcgggcggtggactggtggagcttgggg
gccctgatgtacgacatgctcactggatcgccacccttcactgcagagaaccggaagaaa
accatggacaagatcatcagagggaagctggagctgcctgcctacctcaccccggatgcc
cgggacctcgtcaagaagtttctgaagcggaatcccagccaacgtatcgggggtggcccc
ggggacgccgctgatgtgcagaggcaccccttcttccggcacgttaattgggacgacctc
ctggcccgccgcgtggacccccctttccggccctccctgcagtcggaggaggacgtgagc
cagtttgactcccacttcacgaggcagacgccggtggacagtccagacgacacggccctc
agtgagagcgccaaccaggccttcctgggcttcacgtacgtggcgccctccgtcctggac
agcatcaaggagggcttctccttccagcccaagctgcgctcccccaggcgcctcaacagc
agcccctggacccccatcagccccctgaagttctcgccctttgagggattccggcccagc
cccggcccaccagagcccccggagccccctctaccccctctcctgctcccgctgctgcca
ccaccaccaccctcgagcactgcccccctccccatccgacccccctcagggaccaagaag
tccaagaaaggccgtgggcgccccgggcgctaa

Balaenoptera acutorostrata scammoni (minke whale): 103019799

Entry

103019799 CDS T03086

Gene name

RPS6KB1

Definition

(RefSeq) ribosomal protein S6 kinase B1

K04688

ribosomal protein S6 kinase beta [EC:2.7.11.1]

Organism

bacu Balaenoptera acutorostrata scammoni (minke whale)

Pathway

bacu01521

EGFR tyrosine kinase inhibitor resistance

bacu01522

Endocrine resistance

bacu04012

ErbB signaling pathway

bacu04066

HIF-1 signaling pathway

bacu04140

Autophagy - animal

bacu04150

mTOR signaling pathway

bacu04151

PI3K-Akt signaling pathway

bacu04152

AMPK signaling pathway

bacu04211

Longevity regulating pathway

bacu04213

Longevity regulating pathway - multiple species

bacu04350

TGF-beta signaling pathway

bacu04371

Apelin signaling pathway

bacu04666

Fc gamma R-mediated phagocytosis

bacu04714

Thermogenesis

bacu04910

Insulin signaling pathway

bacu04931

Insulin resistance

bacu05163

Human cytomegalovirus infection

bacu05165

Human papillomavirus infection

bacu05170

Human immunodeficiency virus 1 infection

bacu05200

Pathways in cancer

bacu05205

Proteoglycans in cancer

bacu05210

Colorectal cancer

bacu05212

Pancreatic cancer

bacu05221

Acute myeloid leukemia

bacu05224

Breast cancer

bacu05225

Hepatocellular carcinoma

bacu05226

Gastric cancer

bacu05231

Choline metabolism in cancer

bacu05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

Brite

KEGG Orthology (KO) [BR:bacu00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    103019799 (RPS6KB1)
   04350 TGF-beta signaling pathway
    103019799 (RPS6KB1)
   04371 Apelin signaling pathway
    103019799 (RPS6KB1)
   04066 HIF-1 signaling pathway
    103019799 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    103019799 (RPS6KB1)
   04152 AMPK signaling pathway
    103019799 (RPS6KB1)
   04150 mTOR signaling pathway
    103019799 (RPS6KB1)
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103019799 (RPS6KB1)
09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    103019799 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103019799 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    103019799 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    103019799 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    103019799 (RPS6KB1)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103019799 (RPS6KB1)
   05205 Proteoglycans in cancer
    103019799 (RPS6KB1)
   05231 Choline metabolism in cancer
    103019799 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103019799 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103019799 (RPS6KB1)
   05212 Pancreatic cancer
    103019799 (RPS6KB1)
   05225 Hepatocellular carcinoma
    103019799 (RPS6KB1)
   05226 Gastric cancer
    103019799 (RPS6KB1)
   05221 Acute myeloid leukemia
    103019799 (RPS6KB1)
   05224 Breast cancer
    103019799 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    103019799 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103019799 (RPS6KB1)
   05163 Human cytomegalovirus infection
    103019799 (RPS6KB1)
   05165 Human papillomavirus infection
    103019799 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103019799 (RPS6KB1)
   01522 Endocrine resistance
    103019799 (RPS6KB1)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bacu01001]
    103019799 (RPS6KB1)
Enzymes [BR:bacu01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     103019799 (RPS6KB1)
Protein kinases [BR:bacu01001]
Serine/threonine kinases: AGC group
  RSK family [OT]
   103019799 (RPS6KB1)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal APH

Other DBs

NCBI-GeneID:

103019799

NCBI-ProteinID:

XP_007190341

UniProt:

A0A384ASG2

LinkDB

Position

AA seq 525 aa
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQAPVEYPMETSG
IEQMDVTVSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL

NT seq 1578 nt +upstreamnt +downstreamnt
atgaggcgacgacggaggcgggacggtttttacccagcgccggacttccgagacagggaa
gctgaggacatggcaggagtgtttgacatagacctggaccagccagaggacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggagcattgtgagaaatttgaaatctcagaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgagtacttggtaaaggg
ggctatggaaaggtttttcaagtgcgaaaagtaacaggagcaaataccgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagaacggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagactggtggaaaactctacctcatccttgagtatctcagcggaggagaatta
tttatgcagttagaaagagaaggaatatttatggaagacacagcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgcttaatcaccaaggtcatgtgaaactaacagattttggactatgc
aaagaatctattcatgacggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtggattggtggagtctggga
gcattaatgtatgacatgctgactggagcacccccgttcactggggagaatagaaagaaa
acaattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacacaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtcttggagctggtcct
ggggacgctggagaagttcaagctcatccattcttcagacatattaactgggaagaactg
ctggctcggaaggtagagcccccctttaaacctctgttgcaatctgaagaggatgtgagt
cagtttgattcaaagtttacacgtcagacacctgttgacagcccagatgactcaactctc
agtgaaagtgccaaccaggtctttctgggttttacgtatgtggctccatctgtacttgaa
agcgtgaaagaaaagttttcctttgaaccaaaaatccggtcacctcgaagatttattggc
agcccacggacacctgtcagccctgtcaaattttctcctggggatttctggggaagaggt
gcttcagccagcacggcaaatcctcaggcgcctgtggaatacccaatggaaacaagtgga
atagagcagatggatgtgacggtgagtggggaagcttcagcaccacttccaatacgacag
ccgaactccgggccatacaaaaaacaagcttttcccatgatctccaaacgaccagaacac
ctgcgtatgaatctatga

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