KEGG T03086: 102999446

KEGG Orthology (KO) [BR:bacu00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102999446 (TGFBR1)
   04350 TGF-beta signaling pathway
    102999446 (TGFBR1)
   04390 Hippo signaling pathway
    102999446 (TGFBR1)
   04371 Apelin signaling pathway
    102999446 (TGFBR1)
   04068 FoxO signaling pathway
    102999446 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102999446 (TGFBR1)
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102999446 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    102999446 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    102999446 (TGFBR1)
09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    102999446 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    102999446 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102999446 (TGFBR1)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102999446 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102999446 (TGFBR1)
   05212 Pancreatic cancer
    102999446 (TGFBR1)
   05225 Hepatocellular carcinoma
    102999446 (TGFBR1)
   05226 Gastric cancer
    102999446 (TGFBR1)
   05220 Chronic myeloid leukemia
    102999446 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102999446 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102999446 (TGFBR1)
   05161 Hepatitis B
    102999446 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    102999446 (TGFBR1)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bacu01001]
    102999446 (TGFBR1)
Enzymes [BR:bacu01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     102999446 (TGFBR1)
Protein kinases [BR:bacu01001]
Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   102999446 (TGFBR1)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Pkinase_fungal APH Activin_recp FTA2

Other DBs

NCBI-GeneID:

102999446

NCBI-ProteinID:

XP_007197119

LinkDB

Position

AA seq 438 aa
MCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTVGPFPGKPSSGLGPVE
LAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMT
TSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFRE
AEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKL
ALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTI
DIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQ
LPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTA
LRIKKTLSQLSQQEGIKM

NT seq 1317 nt +upstreamnt +downstreamnt
atgtgtatagctgaaatcgacctaattccacgagacaggccatttgtatgtgcaccatct
tcaaaaactgggtctgttactacaacatattgctgcaatcaggaccattgcaataaaata
gaactcccaactgttggcccttttccaggaaagccatcatctggccttggtcctgtcgaa
ctggcagctgtcattgctggaccagtatgcttcgtctgcatctcactcatgttgatggtc
tatatctgccataaccgcactgtcattcaccatcgagtgccaaatgaagaggatccttcg
ttagatcgcccctttatttcagagggtactacgttaaaagatttaatttatgatatgaca
acatcgggttctggatcaggtttaccattgcttgttcagaggacaattgcgagaactatt
gtgttacaagaaagtattggcaaaggtcgttttggagaagtttggcgaggaaaatggaga
ggagaagaagttgctgttaaaatattctcctctagagaagaacgttcatggttccgtgag
gcagagatttatcagaccgtcatgttacgtcatgaaaacatcttgggatttatagcagca
gacaataaagacaatggtacatggactcagctctggttggtgtcagattatcatgagcat
ggatccctttttgattacttgaacagatacacagttactgtggaaggaatgataaaactc
gctctgtccacagcaagtggacttgcccatcttcacatggagatagttggtacccaagga
aaaccagccattgctcatagggatttgaaatcaaagaatatcttggtaaagaagaatgga
acttgctgtattgcagacttgggactggcagtaagacatgattcggccacagatacaatt
gatattgctccaaaccacagagtgggaacaaaaaggtacatggcccctgaagttctagat
gattccataaatatgaaacactttgaatccttcaaacgtgctgacatctatgcaatggga
ctagtattctgggaaatagctcgacgatgttccattggtggaattcatgaagattaccag
ctgccttattatgatcttgtaccttctgatccatcagttgaagaaatgagaaaagttgtt
tgtgaacagaagttaaggccaaatattccaaacagatggcagagctgtgaagccttgaga
gtgatggctaaaattatgagagaatgttggtatgccaatggagcagctaggcttacagct
ctgcggattaagaaaacattgtcacagctcagtcagcaggaaggcatcaaaatgtaa

Balaenoptera acutorostrata scammoni (minke whale): 103005777

Entry

103005777 CDS T03086

Gene name

TGFBR2

Definition

(RefSeq) transforming growth factor beta receptor 2

K04388

TGF-beta receptor type-2 [EC:2.7.11.30]

Organism

bacu Balaenoptera acutorostrata scammoni (minke whale)

Pathway

bacu04010

MAPK signaling pathway

bacu04060

Cytokine-cytokine receptor interaction

bacu04068

FoxO signaling pathway

bacu04144

Endocytosis

bacu04218

Cellular senescence

bacu04350

TGF-beta signaling pathway

bacu04380

Osteoclast differentiation

bacu04390

Hippo signaling pathway

bacu04520

Adherens junction

bacu04659

Th17 cell differentiation

bacu04926

Relaxin signaling pathway

bacu04933

AGE-RAGE signaling pathway in diabetic complications

bacu05142

Chagas disease

bacu05161

Hepatitis B

bacu05166

Human T-cell leukemia virus 1 infection

bacu05200

Pathways in cancer

bacu05202

Transcriptional misregulation in cancer

bacu05210

Colorectal cancer

bacu05212

Pancreatic cancer

bacu05220

Chronic myeloid leukemia

bacu05225

Hepatocellular carcinoma

bacu05226

Gastric cancer

Brite

KEGG Orthology (KO) [BR:bacu00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103005777 (TGFBR2)
   04350 TGF-beta signaling pathway
    103005777 (TGFBR2)
   04390 Hippo signaling pathway
    103005777 (TGFBR2)
   04068 FoxO signaling pathway
    103005777 (TGFBR2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    103005777 (TGFBR2)
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    103005777 (TGFBR2)
  09143 Cell growth and death
   04218 Cellular senescence
    103005777 (TGFBR2)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    103005777 (TGFBR2)
09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    103005777 (TGFBR2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    103005777 (TGFBR2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103005777 (TGFBR2)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103005777 (TGFBR2)
   05202 Transcriptional misregulation in cancer
    103005777 (TGFBR2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103005777 (TGFBR2)
   05212 Pancreatic cancer
    103005777 (TGFBR2)
   05225 Hepatocellular carcinoma
    103005777 (TGFBR2)
   05226 Gastric cancer
    103005777 (TGFBR2)
   05220 Chronic myeloid leukemia
    103005777 (TGFBR2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    103005777 (TGFBR2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103005777 (TGFBR2)
   05161 Hepatitis B
    103005777 (TGFBR2)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    103005777 (TGFBR2)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bacu01001]
    103005777 (TGFBR2)
Enzymes [BR:bacu01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     103005777 (TGFBR2)
Protein kinases [BR:bacu01001]
Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   103005777 (TGFBR2)

SSDB

Motif

Pfam:

ecTbetaR2 PK_Tyr_Ser-Thr Pkinase Pkinase_fungal APH

Other DBs

NCBI-GeneID:

103005777

NCBI-ProteinID:

XP_007191598

UniProt:

A0A384AWF2

LinkDB

Position

AA seq 549 aa
MLVNHVMHLFSLPVNSDMMVTDDNGAVKLPQLCKFCDVRLSTCDNQKSCWSNCSITAICE
KPQEVCVAVWRKNDENITLETVCHDPKVTYHGFVLDDAASPKCIMKEKKGSGETFFMCSC
SSEECNDHIIFSEEYATNNPDLLLVIFQVTGVSLLPPLGIAIAVIVTFYCYRVHRQQKLS
PAWDSGKPRKLMEFSEHLAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEV
YKAKLRQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELG
KQYWLITAFHAKGNLQEYLTRHVISWEDLRRLGSSLARGIAHLHSDHTLCGRPKMPIVHR
DLKSSNILVKGDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLEN
VESFKQTDVYSMALVLWEMTSRCSAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRP
EIPSSWLNHQGIQMVCETLAECWDHDPEARLTAQCVAERFSELEHLDRLSGRSSSEEKIP
EDGSLNTTK

NT seq 1650 nt +upstreamnt +downstreamnt
atgttggttaatcacgtaatgcatctcttttccctcccagttaacagtgacatgatggtc
actgacgacaatggtgccgtcaagttgccgcagttgtgtaaattctgcgatgtgagattg
tccacctgtgacaaccagaagtcctgctggagcaactgcagtatcacggccatctgtgag
aagccgcaagaggtctgcgtggctgtctggagaaagaatgatgagaacatcacgctggag
acggtctgccatgaccccaaggtcacctaccatggatttgtccttgacgacgctgcttct
ccaaagtgtattatgaaggaaaaaaaggggtctggagagactttcttcatgtgttcctgc
agctccgaagagtgcaatgaccacatcatcttctccgaagaatacgccaccaacaacccc
gacttgctgttggtcatcttccaagtgacaggtgtcagcctcctgccgccgctgggcatc
gccattgctgtcatcgtcaccttctactgctaccgcgtccaccggcagcagaagctgagc
ccggcctgggactcgggcaagccgcgcaagctgatggagttcagtgagcacctggccatc
atcctggaggatgaccgctccgacatcagctccacctgcgccaacaacatcaatcacaac
acggagttgctgcccattgagctggacaccctggtgggcaaagggcgcttcgccgaggtc
tacaaggccaagctgaggcagaacacgtctgagcagtttgagaccgtggccgtcaagatc
ttcccctatgaagaatatgcctcctggaagacggagaaggacatcttctcggacatcaac
ctcaagcacgagaacatcctgcagttcctgacagctgaggagcgcaagacggagctgggc
aagcagtactggctgatcaccgccttccacgccaagggcaacctgcaggagtacctgacg
cgccacgtcatcagctgggaggacctgcgcaggctgggcagctcgctggcccgtggcatc
gcgcacctgcacagcgaccacacgctgtgcggccgacccaagatgcccatcgtgcacagg
gacctcaagagctccaacatcctggtcaagggagacctcacctgctgcctctgtgacttc
ggcctctccctgcggctggaccccactctgtctgtggatgacctggccaacagtgggcag
gtgggaacggcgagatacatggctccagaggtcctagagtccaggatgaatctggagaat
gtcgagtccttcaagcagacggatgtctactccatggccctggtgctctgggaaatgaca
tctcgctgcagcgcagtgggagaagtgaaggattatgagcctccattcggttccaaggtg
cgagagcatccctgtgtcgaaagcatgaaggacaacgtgttgagagatcgaggacgaccc
gaaatccccagctcctggctcaaccaccagggcatccagatggtgtgcgagacgctggcc
gagtgctgggaccacgaccccgaggcccggctcacggcgcagtgtgtggccgagcgcttc
agtgagctggagcatctggacagactctcgggcaggagcagttcggaggagaagattccc
gaagacggctccctgaacactaccaagtag

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