KEGG   Balaenoptera acutorostrata scammoni (minke whale): 103004532
Entry
103004532         CDS       T03086                                 

Gene name
PRKCA
Definition
(RefSeq) protein kinase C alpha
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
bacu  Balaenoptera acutorostrata scammoni (minke whale)
Pathway
bacu01521  EGFR tyrosine kinase inhibitor resistance
bacu04010  MAPK signaling pathway
bacu04012  ErbB signaling pathway
bacu04014  Ras signaling pathway
bacu04015  Rap1 signaling pathway
bacu04020  Calcium signaling pathway
bacu04066  HIF-1 signaling pathway
bacu04070  Phosphatidylinositol signaling system
bacu04071  Sphingolipid signaling pathway
bacu04072  Phospholipase D signaling pathway
bacu04150  mTOR signaling pathway
bacu04151  PI3K-Akt signaling pathway
bacu04261  Adrenergic signaling in cardiomyocytes
bacu04270  Vascular smooth muscle contraction
bacu04310  Wnt signaling pathway
bacu04360  Axon guidance
bacu04370  VEGF signaling pathway
bacu04510  Focal adhesion
bacu04540  Gap junction
bacu04650  Natural killer cell mediated cytotoxicity
bacu04664  Fc epsilon RI signaling pathway
bacu04666  Fc gamma R-mediated phagocytosis
bacu04670  Leukocyte transendothelial migration
bacu04713  Circadian entrainment
bacu04720  Long-term potentiation
bacu04723  Retrograde endocannabinoid signaling
bacu04724  Glutamatergic synapse
bacu04725  Cholinergic synapse
bacu04726  Serotonergic synapse
bacu04727  GABAergic synapse
bacu04728  Dopaminergic synapse
bacu04730  Long-term depression
bacu04750  Inflammatory mediator regulation of TRP channels
bacu04911  Insulin secretion
bacu04912  GnRH signaling pathway
bacu04916  Melanogenesis
bacu04918  Thyroid hormone synthesis
bacu04919  Thyroid hormone signaling pathway
bacu04921  Oxytocin signaling pathway
bacu04925  Aldosterone synthesis and secretion
bacu04926  Relaxin signaling pathway
bacu04928  Parathyroid hormone synthesis, secretion and action
bacu04929  GnRH secretion
bacu04933  AGE-RAGE signaling pathway in diabetic complications
bacu04935  Growth hormone synthesis, secretion and action
bacu04960  Aldosterone-regulated sodium reabsorption
bacu04961  Endocrine and other factor-regulated calcium reabsorption
bacu04970  Salivary secretion
bacu04971  Gastric acid secretion
bacu04972  Pancreatic secretion
bacu05017  Spinocerebellar ataxia
bacu05022  Pathways of neurodegeneration - multiple diseases
bacu05031  Amphetamine addiction
bacu05032  Morphine addiction
bacu05143  African trypanosomiasis
bacu05146  Amoebiasis
bacu05161  Hepatitis B
bacu05163  Human cytomegalovirus infection
bacu05164  Influenza A
bacu05170  Human immunodeficiency virus 1 infection
bacu05171  Coronavirus disease - COVID-19
bacu05200  Pathways in cancer
bacu05205  Proteoglycans in cancer
bacu05206  MicroRNAs in cancer
bacu05214  Glioma
bacu05223  Non-small cell lung cancer
bacu05225  Hepatocellular carcinoma
bacu05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:bacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103004532 (PRKCA)
   04012 ErbB signaling pathway
    103004532 (PRKCA)
   04014 Ras signaling pathway
    103004532 (PRKCA)
   04015 Rap1 signaling pathway
    103004532 (PRKCA)
   04310 Wnt signaling pathway
    103004532 (PRKCA)
   04370 VEGF signaling pathway
    103004532 (PRKCA)
   04066 HIF-1 signaling pathway
    103004532 (PRKCA)
   04020 Calcium signaling pathway
    103004532 (PRKCA)
   04070 Phosphatidylinositol signaling system
    103004532 (PRKCA)
   04072 Phospholipase D signaling pathway
    103004532 (PRKCA)
   04071 Sphingolipid signaling pathway
    103004532 (PRKCA)
   04151 PI3K-Akt signaling pathway
    103004532 (PRKCA)
   04150 mTOR signaling pathway
    103004532 (PRKCA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103004532 (PRKCA)
   04540 Gap junction
    103004532 (PRKCA)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    103004532 (PRKCA)
   04664 Fc epsilon RI signaling pathway
    103004532 (PRKCA)
   04666 Fc gamma R-mediated phagocytosis
    103004532 (PRKCA)
   04670 Leukocyte transendothelial migration
    103004532 (PRKCA)
  09152 Endocrine system
   04911 Insulin secretion
    103004532 (PRKCA)
   04929 GnRH secretion
    103004532 (PRKCA)
   04912 GnRH signaling pathway
    103004532 (PRKCA)
   04921 Oxytocin signaling pathway
    103004532 (PRKCA)
   04926 Relaxin signaling pathway
    103004532 (PRKCA)
   04935 Growth hormone synthesis, secretion and action
    103004532 (PRKCA)
   04918 Thyroid hormone synthesis
    103004532 (PRKCA)
   04919 Thyroid hormone signaling pathway
    103004532 (PRKCA)
   04928 Parathyroid hormone synthesis, secretion and action
    103004532 (PRKCA)
   04916 Melanogenesis
    103004532 (PRKCA)
   04925 Aldosterone synthesis and secretion
    103004532 (PRKCA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103004532 (PRKCA)
   04270 Vascular smooth muscle contraction
    103004532 (PRKCA)
  09154 Digestive system
   04970 Salivary secretion
    103004532 (PRKCA)
   04971 Gastric acid secretion
    103004532 (PRKCA)
   04972 Pancreatic secretion
    103004532 (PRKCA)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103004532 (PRKCA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    103004532 (PRKCA)
  09156 Nervous system
   04724 Glutamatergic synapse
    103004532 (PRKCA)
   04727 GABAergic synapse
    103004532 (PRKCA)
   04725 Cholinergic synapse
    103004532 (PRKCA)
   04728 Dopaminergic synapse
    103004532 (PRKCA)
   04726 Serotonergic synapse
    103004532 (PRKCA)
   04720 Long-term potentiation
    103004532 (PRKCA)
   04730 Long-term depression
    103004532 (PRKCA)
   04723 Retrograde endocannabinoid signaling
    103004532 (PRKCA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103004532 (PRKCA)
  09158 Development and regeneration
   04360 Axon guidance
    103004532 (PRKCA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    103004532 (PRKCA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103004532 (PRKCA)
   05206 MicroRNAs in cancer
    103004532 (PRKCA)
   05205 Proteoglycans in cancer
    103004532 (PRKCA)
   05231 Choline metabolism in cancer
    103004532 (PRKCA)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    103004532 (PRKCA)
   05214 Glioma
    103004532 (PRKCA)
   05223 Non-small cell lung cancer
    103004532 (PRKCA)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    103004532 (PRKCA)
   05022 Pathways of neurodegeneration - multiple diseases
    103004532 (PRKCA)
  09165 Substance dependence
   05031 Amphetamine addiction
    103004532 (PRKCA)
   05032 Morphine addiction
    103004532 (PRKCA)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    103004532 (PRKCA)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103004532 (PRKCA)
   05161 Hepatitis B
    103004532 (PRKCA)
   05171 Coronavirus disease - COVID-19
    103004532 (PRKCA)
   05164 Influenza A
    103004532 (PRKCA)
   05163 Human cytomegalovirus infection
    103004532 (PRKCA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103004532 (PRKCA)
   05143 African trypanosomiasis
    103004532 (PRKCA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103004532 (PRKCA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bacu01001]
    103004532 (PRKCA)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bacu04131]
    103004532 (PRKCA)
Enzymes [BR:bacu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     103004532 (PRKCA)
Protein kinases [BR:bacu01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   103004532 (PRKCA)
Membrane trafficking [BR:bacu04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    103004532 (PRKCA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C2 C1_1 Pkinase_C APH Kinase-like
Other DBs
NCBI-GeneID: 103004532
NCBI-ProteinID: XP_007185612
UniProt: A0A384AE52
LinkDB
Position
Un
AA seq 559 aa
MKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTEEKLHVTVRDAKNLIPMDPN
GLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDR
TTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNMELRQKFEKAK
LGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKI
LKKDVVIQDDDVECTMVEKRVLALMDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHI
QQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHM
MDGVTTRTFCGTPDYIAPEIIAYQPYGRSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQS
IMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHTFFRRIDWEKLENRE
IQPPFKPKVTFCTKMHWLQWASRPSCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDF
EGFSYVNPQFVHPTIQSTV
NT seq 1680 nt   +upstreamnt  +downstreamnt
atgaagtgtgacacctgtgatatgaacgtgcacaagcagtgcgtgataaacgtccccagc
ctctgcgggatggaccacacggagaagaggggccggatctacctgaaggccgaggtcacc
gaggaaaagctccacgtcacagtacgagatgcaaaaaatctcatccctatggatccaaat
gggctttcagatccttatgtgaagctgaagcttattcctgaccccaagaacgaaagcaaa
caaaaaaccaaaaccatccgttccacactgaacccccagtggaatgagtcctttacattc
aaattaaaaccttcagataaagaccgacgactgtccgtagagatctgggactgggatcga
accacccggaacgacttcatggggtccctttccttcggagtctcggagctgatgaagatg
ccggccagtggatggtacaagttgctgaaccaagaggaaggtgagtactacaatgtgccc
atcccagaaggtgatgaagaaggaaacatggagctcaggcagaaattcgagaaagccaag
ctcggccctgctggcaacaaagtcattagtccttctgaggacaggagacagccttccaac
aacctcgacagagtgaaactcaccgacttcaacttcctcatggtgctgggcaagggcagc
ttcgggaaggtgatgcttgcagacaggaaggggaccgaggagctgtacgccatcaagatc
ctgaagaaggacgtggtgatccaggatgacgacgtggagtgcaccatggtggagaagcgg
gtgctggccctgatggacaagcccccgttcctgacgcagctgcactcctgcttccagacg
gtggatcggctgtacttcgtcatggaatacgtcaatggcggggacctcatgtaccacatc
cagcaagtgggaaaatttaaggagccgcaagcagtgttctacgcagcagagatttccatc
gggttgttctttcttcataaaagagggatcatttatagagacctgaagttagataatgtc
atgctggattcggaaggacatatcaagattgcggacttcgggatgtgtaaggagcacatg
atggacggggtcacgaccaggaccttctgcgggaccccggattacatcgccccggagata
atcgcgtatcagccgtacgggagatccgtggactggtgggcctacggcgtcctgttgtac
gaaatgctggccgggcagcctccgtttgacggcgaggatgaggacgaactgtttcagtcc
atcatggagcacaacgtctcgtacccgaagtccttgtccaaggaggccgtttccatctgc
aaagggctgatgaccaaacaccccggcaagcggctgggctgcgggcccgagggagagcgg
gacgtgcgggaacacaccttcttccggaggatcgactgggagaagctggagaacagggag
atccagccgcccttcaagcccaaagtgactttctgcaccaaaatgcactggcttcagtgg
gcgtccaggccttcgtgcggcaaaggagcagagaactttgacaagttcttcacgcgaggg
cagcccgtcctaacgccgcccgaccagctggtcatcgccaacatcgaccagtctgatttt
gaagggttctcgtatgtcaacccccagttcgtgcaccccaccatacagagcacagtatga

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