KEGG   Balaenoptera acutorostrata scammoni (minke whale): 103004642
Entry
103004642         CDS       T03086                                 

Gene name
CASP8
Definition
(RefSeq) caspase 8
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
bacu  Balaenoptera acutorostrata scammoni (minke whale)
Pathway
bacu01524  Platinum drug resistance
bacu04115  p53 signaling pathway
bacu04210  Apoptosis
bacu04215  Apoptosis - multiple species
bacu04217  Necroptosis
bacu04620  Toll-like receptor signaling pathway
bacu04621  NOD-like receptor signaling pathway
bacu04622  RIG-I-like receptor signaling pathway
bacu04625  C-type lectin receptor signaling pathway
bacu04657  IL-17 signaling pathway
bacu04668  TNF signaling pathway
bacu04932  Non-alcoholic fatty liver disease
bacu05010  Alzheimer disease
bacu05016  Huntington disease
bacu05022  Pathways of neurodegeneration - multiple diseases
bacu05132  Salmonella infection
bacu05134  Legionellosis
bacu05142  Chagas disease
bacu05145  Toxoplasmosis
bacu05152  Tuberculosis
bacu05160  Hepatitis C
bacu05161  Hepatitis B
bacu05162  Measles
bacu05163  Human cytomegalovirus infection
bacu05164  Influenza A
bacu05165  Human papillomavirus infection
bacu05167  Kaposi sarcoma-associated herpesvirus infection
bacu05168  Herpes simplex virus 1 infection
bacu05169  Epstein-Barr virus infection
bacu05170  Human immunodeficiency virus 1 infection
bacu05200  Pathways in cancer
bacu05203  Viral carcinogenesis
bacu05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:bacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    103004642 (CASP8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    103004642 (CASP8)
   04215 Apoptosis - multiple species
    103004642 (CASP8)
   04217 Necroptosis
    103004642 (CASP8)
   04115 p53 signaling pathway
    103004642 (CASP8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103004642 (CASP8)
   04621 NOD-like receptor signaling pathway
    103004642 (CASP8)
   04622 RIG-I-like receptor signaling pathway
    103004642 (CASP8)
   04625 C-type lectin receptor signaling pathway
    103004642 (CASP8)
   04657 IL-17 signaling pathway
    103004642 (CASP8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103004642 (CASP8)
   05203 Viral carcinogenesis
    103004642 (CASP8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103004642 (CASP8)
   05016 Huntington disease
    103004642 (CASP8)
   05022 Pathways of neurodegeneration - multiple diseases
    103004642 (CASP8)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    103004642 (CASP8)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    103004642 (CASP8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103004642 (CASP8)
   05134 Legionellosis
    103004642 (CASP8)
   05152 Tuberculosis
    103004642 (CASP8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103004642 (CASP8)
   05161 Hepatitis B
    103004642 (CASP8)
   05160 Hepatitis C
    103004642 (CASP8)
   05164 Influenza A
    103004642 (CASP8)
   05162 Measles
    103004642 (CASP8)
   05168 Herpes simplex virus 1 infection
    103004642 (CASP8)
   05163 Human cytomegalovirus infection
    103004642 (CASP8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103004642 (CASP8)
   05169 Epstein-Barr virus infection
    103004642 (CASP8)
   05165 Human papillomavirus infection
    103004642 (CASP8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103004642 (CASP8)
   05142 Chagas disease
    103004642 (CASP8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    103004642 (CASP8)
Enzymes [BR:bacu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     103004642 (CASP8)
Peptidases and inhibitors [BR:bacu01002]
 Cysteine peptidases
  Family C14: caspase family
   103004642 (CASP8)
SSDB
Motif
Pfam: Peptidase_C14 DED Dynamin_N
Other DBs
NCBI-GeneID: 103004642
NCBI-ProteinID: XP_007190583
UniProt: A0A384AT72
LinkDB
Position
Un
AA seq 486 aa
MNFNRCLYNIGEQLASEDLAALKFLSLDYIPHRKQEPIKDALMLFQRLQEKRMLEESNLS
FLKELLFRMNRLDLLLTYLDTSEEEMERELQMPGRAQISAYRVMLFQISEDVTKLELKDF
KFFLSQEIAKCKLDDDMTLLDIFIEMEKRVILGERNLDTLKRICEQINRSLLKKINDYEE
LSREQRMSLERGPDEFSNDVSQLLIREGSLEMLAMSDSPGEKDSESQTSNTVYRMKSKPR
GYCLIFNNYDFSIARKDVPKLHSIKDRNGTDLDAEALRKTFSELHFEIVHYKDYTAKKIC
EVLKSYQSMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLLGKPK
IFFIQACQGDNYQRGIAVETDSEQKEAYLEMDSSLQKRYIPDEADFLLGMATVNNCVSYR
STMEGTWYIQSLCQSLRERCPRGEDILTILTKVNFEVSNKDDKKNMGKQMPQPTFTLRKK
LFFPLN
NT seq 1461 nt   +upstreamnt  +downstreamnt
atgaatttcaacagatgtctctataatattggggaacagctggccagtgaagacctggct
gccctcaagttcctgagcctggactacattccacataggaagcaggaacccatcaaggat
gccttgatgctattccagaggctccaagaaaagagaatgttggaggaaagcaacctgtcc
ttcttgaaggagctgcttttccgaatgaatagactggatctgctgctcacctacctggac
accagtgaggaggagatggagagggaacttcagatgccgggcagggcccagatctctgcc
tatagggtcatgctttttcagatttcagaagatgtgaccaaactggaattgaaggacttc
aagttttttttgagccaggagatcgccaaatgtaagctggatgatgacatgaccttgctt
gatatcttcatagagatggagaagagggtcatcctaggggaaagaaacttggacaccctg
aaaagaatctgtgagcaaatcaacaggagcctgctgaagaaaatcaacgattatgaagaa
ctaagcagagagcaaagaatgagccttgaaagaggtccagatgaattttcaaacgatgtg
tcacaattgctcataagggagggctctcttgaaatgctggccatgtcggactctccagga
gaaaaagacagtgagtcgcagacatcgaacacggtttaccgaatgaaaagcaaacctcgg
ggatactgtttgatctttaacaattatgattttagcatagcaaggaaggatgtgcccaaa
cttcacagcattaaggataggaatggaacagacttggatgcagaggctttgagaaagacc
tttagtgagcttcattttgagatagtgcattacaaagactacactgcaaagaaaatctgt
gaggttctgaaatcctaccaaagcatggaccacaataacaaggactgcttcatctgctgc
atcctctcccatggagacaagggcatcatctatggctccgatgggcaggaagcccctatc
tatgagctgacctcttacttcactggttcaaagtgcccttcccttcttggcaaacccaaa
atcttttttattcaggcttgtcaaggggataactaccagagaggtatagctgttgagact
gactcagaacagaaggaagcctatttagaaatggattcatcacttcagaagagatatatc
ccagatgaggctgactttctgctggggatggccaccgtgaacaactgtgtttcctaccga
agcaccatggaggggacctggtatatccagtcactttgccagagcctgagagaaagatgt
cctaggggtgaagatattctcaccatcctcaccaaggtgaactttgaagtaagcaataag
gatgacaagaaaaatatgggcaaacagatgccacaacctactttcacactgagaaaaaaa
ctcttctttccccttaattga

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